<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04321

Description Uncharacterized protein
SequenceMALIAALKYDDTKKEGDRLRDISPCISECERLFHIIYKYLTSKSLEHLFQENLDFIERNQKLTIIECYRLLEHMSNNDKRGLALKFCIENLQMCEEIKGRQFEFEEILTFIINKLYKNQLLHHFHCFELHVLNTDYKLKIPIDKRKFTFMKENIHLLDYKEKRNIMKSLLVEKFEHIPMHLTEIQRQHVLPIEELILEIIDRENNYIPPLFTITEVFRLTLTSTAYLFPRISKKLVNMMSSFRPLAEMITPIGRPWLFPIISHIGYNSSNNTWKLTDGPVNKIVSKAHLPYSTEYMTSQSYFLYMVLKQPRGNVMMKSMLAKTNSIGPNNKLNITELLQLFILEAMYECEITTLPTHHPAVQYTWLNLQHLSEFCLFHSNVFFLDLLKLLRKSLMELKYRKARDELMWLFLQHVTINVGKFQRECMIEIAEIYKILYTGNEAWVGSSLDVMKMIKFFAPAAIWVCYEKDNKEEFPKPNSIIKNHMELFKREAEKGSELHDGMLIVIGNAISTDKVNFQEKFYKVLMKQLQGNEDEEKWLLPYGRKVDKRLKAIELTSLDCFTFHAKDMTVKHLMYLFGPSNPTLYTVSPAIIESLIRIIMSVEVFDSTKFQLLNMLGYYVKNDDLDLTYVIAEAICFRVIDIHMHYSQRVTVVRSVIEGLRRLTPQDSSNYMFFILEQLFIRTFMWCNQHDMCQLLIKSLNDKTIGINSHICSSVSQFTGDIDNISMLISPEVVKMLYFIFMKNIKLTGIDIPFELVKTINENYRFPPSFAKHLYNNSDEFNSQTTVEDNNLNMLIDLINNDPFLKEIKFPEEYLSKYRDKYILFCVIFKFLEDNPDSEFNPCFYKILTHFNPKEIVLLCNNFIEYLIHRFKNIEKDEIEKLTKIINDMIFKYQITTFDKFLTSLVMHPNDDSSNITSLDFLYYLLTTCNDLQQKLNACLSFIPRREFVCRADSEKFFKKMSLYHKNFPEYTYKELLQRLEKKEDFTIPELHLPIYYKNLAELILPTIDMMFTKAILLNYNFERFVVILKMFSPIYAYHPAPLSFVYGILFLLNCSQLEEPSVFQVFTKKIMSVSQSVKSFTAEFYDNDYFVYSSAYQTCTEIVGKLVEACNIKLIPPKYVSRDWRFSEFAPAGQALYTGAIEIMFTNFPPEIIAESLLDIAIPKSGENYHEKINAACSILTVLPMKYQEYIFTFMQNAITSKELVCCESPELVFSKIEDIIYHCHDNDFIPHLAVIQTFWQLASMAMYTRGIDFFGEVIVNLVTNESQLLYTARIILPFIVKMSEARDKFKKDETIKCTIALYDMISKICGNTETPIVYKSLICDIMYFIKYMFIGDVVKEKAEDVIKKMPKHMQELMKFYNSTGSNVEGSGKLSNTSISLLANQNRLLQRFPAPLDSEEILNDQDNTANNHFDMLNSVQFNRNMNHQLPQVYENIINKSDTTENRMPHPQSSEYKNQQLFNSQHPYNNPNQGNVPNANQRLQMEGRPDHGQVPRSEGVPSHMMPSQKMPQVGMPPNQNVGSQMPMQTGQNMFPGDPRLQQEIRMQQKQQAFQHQYNLHQSMQNKQQQMSHQSNVNQGTNQQMNPYNNPSQYHNVMHGQGIPYNQHIPGKQQQIQPPPGMGPNFNMPPGMNMYNNTQQYPPNMMHHPGMGMHPGVQNPHNIPQQGISPIYSQGHMYQGMPTQQQYPPSHLQGHGYNQQRM
Length1701
PositionTail
OrganismStrongyloides venezuelensis (Threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.11
Grand average of hydropathy-0.305
Instability index51.93
Isoelectric point6.62
Molecular weight199070.22
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04321
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     366.37|      43|      44|    1551|    1593|       1
---------------------------------------------------------------------------
 1356- 1396 (31.89/11.81)	............QEL..MK....F..Y.........NSTGSNV.....EGSGKLSNTSiSLLA.NQNRL.LQR....FPAP
 1397- 1453 (35.02/13.75)	LDSeeilndqdnTAN..NH.......F.........DMLNSVQfnrnmNHQLPQVYEN.IINKsDTTEN.RMP....HPQS
 1454- 1506 (35.01/13.75)	SEY......knqQLFnsQH....P..YnnpnqgnvpNANQRLQ.....MEGRPDHGQV.PRSE.GVPSH.MMP........
 1507- 1538 (49.00/22.45)	SQK........mP..........Q..V.........GMPPN.Q.....NVGSQMPMQT......G..QN.MFP.....GDP
 1548- 1590 (77.32/40.08)	QKQ.........QAF..QH....Q..Y.........NLHQSMQ.....NKQQQMSHQS.NVNQ.GTNQQ.MNP....YNNP
 1591- 1637 (59.80/29.17)	SQY.........HNV..MHgqgiP..Y.........NQH..IP.....GKQQQI..QP.PPGM.GPNFN.MPPgmnmYNNT
 1638- 1663 (37.08/15.04)	QQY........pPNM..MH....HpgM.........GMHPGVQ.....N.......................P....HNIP
 1664- 1701 (41.24/17.62)	QQG........iSPI..YS....Q..G.........HMYQGMP.....T.QQQYPPSH.LQGH.GYNQQrM..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     451.29|     121|     127|     888|    1013|       2
---------------------------------------------------------------------------
  765-  869 (127.29/79.03)	............RFPPSFAKHLYNNSDEFNS.........QTTVED..NNLNMLIDLI.........NNDPFLKEIKFPEEYLSKYR..DK...YILfcvifKFLEDNPD....SEFN.PCFYKilthfNPKEIVLlcnNFIEYLIH
  888- 1013 (196.46/143.66)	DMIFKYQittFDKFLTSLVMHPNDDSSNITSLDFLY..YLLTTCNDLQQKLNACLSFIPRReFVCRADSEKFFKKMSLYHKNFPEYT..YK...ELL.....QRLEKKEDF.TIPELHlPIYYK.....NLAELIL...PTIDMMFT
 1015- 1120 (127.54/80.04)	AILLNYN...FERFVVILKMFSPIYAYHPAPLSFVYgiLFLLNCSQLEE..PSVFQVFTKK.IMSVSQSVKSF.TAEFYDNDYFVYSsaYQtctEIV.....GKLVEACNIkLIP....PKY.........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.50|      30|     127|      36|      72|       3
---------------------------------------------------------------------------
   36-   66 (45.26/40.44)	IYKYLTSKSLEHLfQENLDFIERNQKLTIIE
  165-  194 (51.24/27.94)	IMKSLLVEKFEHI.PMHLTEIQRQHVLPIEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.80|      37|      42|     557|     598|       5
---------------------------------------------------------------------------
  557-  598 (57.24/38.82)	SLDCftFhakDMTVKHLMYLFG..PSNPTL...YTVSPAIIESLIRI
  601-  642 (53.56/25.23)	SVEV..F...DSTKFQLLNMLGyyVKNDDLdltYVIAEAICFRVIDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.79|      42|      44|    1156|    1199|       7
---------------------------------------------------------------------------
 1156- 1199 (67.24/40.64)	ESLLDIAIPKSGENYHEKINAACSILTVLPmkYQEYIFTFMQNA
 1203- 1244 (76.55/41.05)	KELVCCESPELVFSKIEDIIYHCHDNDFIP..HLAVIQTFWQLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.77|      15|      29|     219|     233|       9
---------------------------------------------------------------------------
  219-  233 (25.64/13.52)	LTLTSTAYLFPRISK
  249-  263 (30.13/17.19)	ITPIGRPWLFPIISH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.95|      31|      48|     441|     476|      10
---------------------------------------------------------------------------
  441-  476 (48.21/41.74)	EAWVGSSL.DVMKMIkfFAPAaiwVCYEKDN.KEEFPK
  491-  523 (44.74/24.64)	EAEKGSELhDGMLIV..IGNA...ISTDKVNfQEKFYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.47|      23|     132|    1124|    1146|      11
---------------------------------------------------------------------------
 1124- 1146 (40.89/28.26)	DWRFSEFAPAGQALYTGAIEIMF
 1258- 1280 (35.58/23.56)	EVIVNLVTNESQLLYTARIILPF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04321 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQLPQVYENIINKSDTTENRMPHPQSSEYKNQQLFNSQHPYNNPNQGNVPNANQRLQMEGRPDHGQVPRSEGVPSHMMPSQKMPQVGMPPNQNVGSQMPMQTGQNMFPGDPRLQQEIRMQQKQQAFQHQYNLHQSMQNKQQQMSHQSNVNQGTNQQMNPYNNPSQYHNVMHGQGIPYNQHIPGKQQQIQPPPGMGPNFNMPPGMNMYNNTQQYPPNMMHHPGMGMHPGVQNPHNIPQQGISPIYSQGHMYQGMPTQQQYPPSHLQGHGYNQQRM
1428
1701










Molecular Recognition Features






MoRF SequenceStartStop




NANANA