<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04316

Description Uncharacterized protein
SequenceMFNSNRSYKVTNWNTESSEKRPIRKASRGRHFDIFPQDSKQDEDNLSSHDRIRKGYIYPQHSYEHESLIYNQKISKIDSKLEDTIKKANNFLITIMRKRSYDNPKSGKRSLVTKAFTVNEWNFLNKIPKCPSIPQFFEDLSKGKALYGLIKRFPQFDKNEDFLKYLFDYRVPIVKAIWFIKIVAIFKATHIPIISKPPKKSQALQSALEYVQSLISGLIIYTFNNFYNDDKNEDEKSDRWNYFSLLIKHMCEEGVLDRQDFLTDMIDLLNKYQNFPLDKPQRFKILFLFVSQFIHYVTQNIIISRRMAFIICRRFQQYHYDYMNITGKPLTAGESLTEIIKCENHRGIINSMTGMLYSIITECPQALPRKHMIYIKKFTGVKIYDELGGSPLDELSCPFDIMCKEANLLPPKLIELMKPKINEIIERSIDMKYQWHEVISGKTYCSELVNIILKILETLDNVFLLNDEELINLHDDILKCTMKMDDNIEIILRRRMLIHWSITSQRDGTHRVSLVVRLFSIHLKDVSDKSKVMINILNDYIYSEAPKLGYCNYGYEFRNFILLLNDFQSFGLISYKKLLDYWIKKGRIEKDNCLWRKTIKYVYGENYERDFHPTWNKNISMSSRYALQFYRRDSEKHTLLNLEGVTPEERIILQLPILPSIYNREDIYFRDKLMFGISIQKNEHINYIKEIARGIIKVWKKLYYFKIETNKTNIHFHEYHDIKGYKNCGDILRRFRRQTYYDQTLITYWVSDNFKEYLVTFIENTNDILPGSDGLDYILRMFCISMNIGGMINYILEILPKISKLEDIMLNRYYNFIPGIITKGYAFTIVAYLSEHLLYFLNHPNAISIINGLYQTIENTITLQSYPRTGYDANISVFISQCKYYLIIHGLAKPNQLLGCVEDFEKLYPKKFIDIKIEQPRVQVKKYFFSKYLNSAPTLLPFNEIRSLIKGVNNNGINCRISFVLSAINIIKTLGRKINKISAVANYCANVSALLNLENEWISAIVELCSISNNPQSMYRGVHKIFNVSRTTTHYALSTFVAILAARFTFRPHELIGKLIKSSLVYAFRGTYNRSKYGYQKVILSALICTKIVTGYHDPFKLPRGYSGLTEVKRPIVKKLSDFKACNVLFPRELDSVIFPLIRLFVMVNRPIRKLRKNRAPKKIRVNHFLRACLLFISEQPWFYQKMHFGILNRDGNWQQFKKILLKNFGIPGILLNYISRRKGDRRAKLMNISCAENSSKKAYIERCLSSLNIWNFKTVFWDLWGIMTDSTRRPQMKNYPQRIYYCDQLITEIAKGISDVFVKTSNSFKKHIDFKTDTRFRLETIKNLYLIENLVMMFPKVWIPRTRSAYYKMHVTTLSAAVLKEFSFIITSKYTKNNYALRMEQMSHLLHITPFLKFLQTILNKEPQTTYALLQGLYGYLSSLMKDFVSRRLLRSHLISDKEGLILRVIIVAGMMDQLSTMPTMEPWAILFWQLLYFEVFHPEREGKFYNICYDALTNVLFNSAFKFQSRHIEHAYYRARYWTYMQFCKKLKKEGQDRPFTVDKQHLSQLLPLPKRTFDYILFDHYYKMIGKAKNTYNVGCSSSNAMKLINRTGYYPVEKIKLTTFETVQSFFHELLGRKTVNYSFYQAVLADYVPKVSIDLLIRLSFHDHYRLFPRAPIIGEGKELTKNFMYRHPEVEITIIPKEEKDKEKIKLMPPRPLMNPSISTNSTITSNPQIAAILAHTPDKPSSSPGSIIKDSQNIPIDIKQPLSDMPKISKEVMHDVNFPSIPQNGPGHIGSIQSKPPNLIDQASHSIDQLNQVPPLSKHKNESPNKNEIISQQISQNSIQQSSMHNRHILSNDLQQMISSNLSNVKKSQQSYNSSQHPIQKSFSSQDVGMGIQLSEINSGNNNMTQKKMHFNDERTFSRDMPQQEPMQTDSQPPVLIASGNLGKGNRRRPHPNPNSGIKTPTKKRKDLKGNDLLSPPILHENQPTMVQSGQQPINMRSFDNNQQAQQLPNFGNQGSFNSQGNMGLSQNITHKNNIPNQGNILNQSGMPGQSNINNQGNIPNQGSLVSQGNMYNQGNISSQNNVHEQSNHSNQNSHHQSQGMHHNQGSHLNQNTSHQTSQLNQNNSNIGMNQQQPSNMFITNSGPSKIASQNQPQSRLPQQNVNSINLPRNPQTGSVNISGGPTSNSINMLGLQQSNNMNHPVHQQQSQNLINMVGSQKSSSINIESHQQGNMVGVSNSQHGSITNISNNQINNMNMPSQPQNSSLSRSNHSSQQQPPPYNMSLNQQASSMNLPSNQQQSTSMTMQGNISGNSINMPSNQQRNMMGVTDNRHNNTMNMSVNQQNSNMNIPPNQQNITMNMPSGQQQSSNIPKNNILQQVLNNPNTTQNIPPNQQYNKNLGITNNPQQGAIQQQQQQKSMMSSNNQSSNVPSHVQQNINSGMRQTSMGQQQSSMQQNINQKMYGQNNNSGMQKPLGQNIMGLGMKPQNLPGPQPHQQQTQQQSSGSGNMPSNMLNNMNTNIQNNMGTSMNSGISSNISGNMASGMSNNNNIPSNMSSSMHSNMSNQQRMIHQNMINQQTQQQQQQIAQQRHIQDGGLPLQQQQRLQQMGNSQQQISGNQNQISNQRGSMHNPQQQQPISGMQQQMSGHHQQIPGHQQQIPPMQQQMHNQQQQSLSSQQQIGNPPQIMGNPNQSMMSSSQQQHWNIQHPQQGSINKEMQGINPNRMSSINSNMVIDRGNMRAGSEAPLETKKLLKDMLKQKTNPGPGMHLPCQQLSQSMMGSQQQGGPPSQHQQIGMGTSGQAQHNQGPIMNTFEPSQRQEMLYRNSQQHQNVNMGMINQQQPQQCNQTQQQYNSQQMYP
Length2848
PositionKinase
OrganismStrongyloides stercoralis (Threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.08
Grand average of hydropathy-0.631
Instability index57.76
Isoelectric point9.61
Molecular weight327899.61
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04316
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     194.98|      26|      27|    2495|    2520|       1
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 2093- 2116 (29.19/ 8.76)	H.......HNQG.SHL..NQNTS.............HQTSQLNQNNS
 2495- 2520 (51.95/23.52)	S.......GNMP.SNMLNNMNTN.............IQNNMGTSMNS
 2527- 2550 (36.31/13.38)	S.......GNMA.SGMSNN..NN.............IPSNMSSSMHS
 2605- 2621 (25.52/ 6.38)	S.......GN.........QN.Q.............ISNQRGSMHNP
 2622- 2661 (25.93/ 6.65)	Q.......QQQPiSGMQQQMSGHhqqipghqqqippMQQQMHNQQQQ
 2662- 2690 (26.08/ 6.75)	SlssqqqiGN.P.PQIMGNPN................QSMMSSSQQQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     140.28|      27|      27|    2027|    2053|       2
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 2012- 2041 (39.45/12.28)	GNMGLSQNITHKnniPNQGNILNQSGMPGQ
 2042- 2071 (37.33/11.19)	SNINNQGNIPNQgslVSQGNMYNQGNISSQ
 2227- 2250 (31.13/ 7.99)	SN.SQHGSITNI...SN..NQINNMNMPSQ
 2819- 2845 (32.36/ 8.62)	QNVNM.GMI.NQ.qqPQQCNQTQQQYNSQQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     164.14|      21|      21|    2320|    2340|       3
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 2260- 2281 (26.37/ 6.60)	NHS.SQQQP..ppyNMSLNQQASSM
 2294- 2315 (26.44/ 6.64)	TMQgNISGNSI...NMPSNQQRNMM
 2316- 2337 (27.50/ 7.24)	GVTdNRHNNTM...NMSVNQQNSNM
 2338- 2358 (30.21/ 8.76)	NIPpNQQNITM...NMPSGQQQSS.
 2757- 2776 (27.82/ 7.41)	HLP.CQQ.LSQ...SMMGSQQQGGP
 2777- 2796 (25.79/ 6.28)	PSQ.HQQ.IGM...GTSGQAQHNQG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     180.77|      26|      27|    1808|    1833|       4
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 1785- 1811 (26.50/ 6.41)	SKP.PNLIDQASHSIDQlNQVPPLSKH..K
 1812- 1837 (41.78/15.40)	NES.PNKNEIISQQISQ.NSIQQSSMH..N
 2132- 2154 (26.47/ 6.39)	NSG.PSK..IASQNQPQ.SRLPQQNVN...
 2388- 2413 (27.04/ 6.72)	NLGiTNNPQQGA..I.Q.QQQQQKSMMssN
 2444- 2466 (30.53/ 8.78)	QQ..NINQKMYGQN..N.NSGMQKPLG..Q
 2551- 2571 (28.45/ 7.56)	NMS..NQQRMIHQNMIN.QQTQQQ......
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     298.64|      95|     107|     599|     705|       5
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  594-  697 (149.63/138.55)	LWRK.tikyVYGENYERDFHPTWNKNISMSSRYALQFYRRDS.EKHTLLNlEGVTP..EERIILQL....PILPSiYNREDIYFRdklMFGISIQKNEHINYIKEIARGIIK
  698-  804 (149.01/122.35)	VWKKlyyfkIETNKTNIHFHEYHDIKGYKNCGDILRRFRRQTyYDQTLIT.YWVSDnfKEYLVTFIentnDILPG.SDGLDYILR...MFCISMNIGGMINYILEILPKISK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.76|      53|     102|     135|     191|       6
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  135-  191 (79.60/67.58)	QFFEDLSKGKALYGLIKRfPQFdkNEDFLKYLFDYR.VPIVKAIWFiKIVAIFKATHI
  241-  294 (90.16/59.59)	NYFSLLIKHMCEEGVLDR.QDF..LTDMIDLLNKYQnFPLDKPQRF.KILFLFVSQFI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.70|      40|     105|     444|     486|       8
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  444-  486 (59.23/41.93)	YCS...ELVNIILkILETLDNVFLLNDEELINLHddILKCTMKMDD
  550-  592 (66.47/36.92)	YCNygyEFRNFIL.LLNDFQSFGLISYKKLLDYW..IKKGRIEKDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     176.13|      39|      41|     849|     889|       9
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  809-  843 (58.58/37.51)	MLNRYYNFIPGIIT......KGYAFTIVAYLSEHLLYFLNH
  849-  889 (63.36/47.84)	IINGLYQTIENTITLqsYPRTGYDANISVFISQCKYYLIIH
  893-  928 (54.18/34.03)	KPNQLLGCVEDFEKL..YPKKFIDIKIEQPRVQVKKYF...
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     121.80|      21|      38|    2167|    2187|      10
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 2168- 2189 (33.34/16.44)	N..ISGGPTSNSIN..MLGLQQ...SNnM
 2190- 2213 (28.07/12.26)	NhpVHQQQSQNLIN..MVGSQK...SSsI
 2426- 2443 (32.05/15.42)	N..INSGMRQTS.....MGQQQ...SS.M
 2693- 2717 (28.34/12.47)	N..I.QHPQQGSINkeMQGINPnrmSS.I
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     218.07|      51|     203|    1730|    1780|      11
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 1690- 1720 (44.42/17.52)	..........KDKEKIKLMPPRPLMN.PSIST....NSTITSNPQ.....I
 1730- 1780 (93.34/45.44)	KPSSSPGSIIKDSQNIPIDIKQPLSDMPKISKEVMHDVNFPSIPQNGPGHI
 1940- 1985 (80.30/38.00)	RPHPNPNSGIK....TPTKKRKDLKGNDLLSPPILHE.NQPTMVQSGQQPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.69|      23|      27|    1471|    1495|      12
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 1471- 1495 (40.73/30.49)	ILFWQLLYFEVFHPEREgkFYNICY
 1501- 1523 (41.96/24.78)	VLFNSAFKFQSRHIEHA..YYRARY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.29|      47|     204|    1191|    1249|      13
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 1191- 1249 (64.10/77.12)	ILNRDgnwQQFKKILLKN.FG.IPGILLNYISRRKgdRRAKLMniscaenSSKKAYIERCL
 1403- 1451 (70.20/47.66)	ILNKE...PQTTYALLQGlYGyLSSLMKDFVSRRL..LRSHLI.......SDKEGLILRVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.44|      36|      37|    1842|    1878|      15
---------------------------------------------------------------------------
 1842- 1864 (27.78/ 8.29)	.................SNDLQQMISSNLSNVKKSQQSYN
 1865- 1903 (51.12/25.74)	SSQHPIQKSFSSqDvgmGIQLSEINSGN.NNMTQKKMHFN
 1909- 1933 (36.55/13.63)	SRDMPQQEPMQT.D...SQPPVLIASGNL...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     163.47|      37|      91|    1544|    1580|      17
---------------------------------------------------------------------------
 1524- 1543 (22.56/ 8.65)	..................WTYMQ...F.CKKL.....KKEGQDR...PFT
 1544- 1580 (65.83/40.07)	VDKQHLSQLLP..LPKRTFDYIL...F.DHYY.....KMIGKAK.N.TYN
 1581- 1609 (40.75/21.86)	VGCSS.SNAMK..LINRT...........GYY.....P.VEKIKlT.TFE
 1624- 1672 (34.34/17.21)	VNYSFYQAVLAdyVPKVSIDLLIrlsFhDHYRlfpraPIIGEGK.ElTKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.17|      10|      42|    2595|    2604|      18
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 2595- 2604 (19.89/ 6.87)	QQMGNSQQQI
 2639- 2648 (21.28/ 7.89)	QQIPGHQQQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.52|      26|      42|    1284|    1313|      19
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 1284- 1313 (39.24/28.72)	IYYCDQLITEIAKgisdVFVKTSNS..FKKHI
 1329- 1356 (43.29/22.57)	LYLIENLVMMFPK....VWIPRTRSayYKMHV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04316 with Med12 domain of Kingdom Metazoa
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