<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04308

Description Uncharacterized protein
SequenceMIDTKFRDELASKRERVELLYSFRGSKIGRGTYGHVYKATPRFETPENKGKTYALKLIEGNGISMSSCREIALLRELSHPNLIKLNRVFLSPERKVWLLFDYAEHDLWHIIKFHRNAKQKKQAVMVPKSMVKSLLFQILDGIHYLHTNWILHRDLKPANILVMGDDPYERGRVKVADMGFARTFHTPVRPLADLDPVVVTFWYRAPELLLGAKHYTKAIDIWAIGCIFAELLTSEPVFFCREEDIKASSPYHKDQLSRIFQVMGYPQDADWPDLKKMPEYQRLSKDFKRQTFSECALYKYLEKHKVKTNDKGFSLLQKLLTFDPLKRISAIDAINDAFFKESPKPTLDVFRGGPIPYPRREFMQDENEEKIIGKHIPQQNIQIQQHLINNIGTNKLVQQGNNQVRQISEPDIKSNQFSNITMTNQTEFNHLNNHSGNLNQPPPQQVNVFNDGNQQNVVQMQQNQYNQQQFITGHDQNRMILQQQQQQPVVQNTIRGPNGQFISQQQSRIISQDQNRMMIQQNQHQFGQQQQQQLFVSHDQNRMMIQQPGRMIQSQGQNNMIPMQQQYIQQQQQQQQQQHQVPSQQQQQQQQQQQMMQQQNFMWNQQQRYQ
Length610
PositionKinase
OrganismStrongyloides stercoralis (Threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.09
Grand average of hydropathy-0.817
Instability index50.36
Isoelectric point9.44
Molecular weight71821.83
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04308
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.91|      17|      19|     561|     578|       1
---------------------------------------------------------------------------
  524-  540 (28.76/ 7.22)	H.QFGQQQQQQL..FVSHDQ
  567-  586 (26.14/ 8.81)	YiQQQQQQQQQQhqVPSQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     145.84|      31|      36|     455|     485|       2
---------------------------------------------------------------------------
  384-  409 (28.88/ 6.80)	....QQHL..INNIGTNKLV..QQGN.NQVRQ....ISE
  410-  443 (31.16/ 7.85)	PDIKSNQFsnITMTNQTEFNhLNNHS.GNLNQ....PPP
  463-  498 (46.64/14.97)	NQYNQQQF..ITGHDQNRMI.LQQQQqQPVVQntirGPN
  541-  565 (39.16/11.53)	NRMMIQQ........PGRMI.QSQGQ.NNMIP....MQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.83|      25|      26|      61|      85|       3
---------------------------------------------------------------------------
   58-   82 (42.69/30.75)	IEGNGISMSSCREIALLRELSHPNL
   83-  107 (44.13/32.02)	IKLNRVFLSPERKVWLLFDYAEHDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.14|      23|      39|     191|     217|       4
---------------------------------------------------------------------------
  191-  217 (33.50/39.05)	LADL...DPVvvtFWYRAPELLlGAKHYTK
  228-  253 (37.65/28.09)	FAELltsEPV...FFCREEDIK.ASSPYHK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.56|      11|      76|     512|     522|       7
---------------------------------------------------------------------------
  512-  522 (22.28/ 8.60)	QDQNRMMIQQN
  590-  600 (23.28/ 9.31)	QQQQQMMQQQN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04308 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQGNNQVRQISEPDIKSNQFSNITMTNQTEFNHLNNHSGNLNQPPPQQVNVFNDGNQQNVVQMQQNQYNQQQFITGHDQNRMILQQQQQQPVVQNTIRGPNGQFISQQQSRIISQDQNRMMIQQNQH
2) QQQQQQLFVSHDQNRMMIQQPGRMIQSQGQNNMIPMQQQYIQ
398
528
524
569










Molecular Recognition Features






MoRF SequenceStartStop




NANANA