<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04307

Description Uncharacterized protein
SequenceMNIEESLKKDLVNDILELDKKMSSLFENVFKKKDEEEESKRENFKCLVNDISKIEIEIIKKLKSTPCIEKTQKKIKKMKAEINKYDKAILKTEAGLIRIFGSVTNSLNIAQKKLCELKKSQQQHNTKTDILEMSKILTKNYTISAPPFYKADDYVKPFPTGVQFIRGSLKHSIPLKDISKKCGVENPTINMLHNVKNIQQHDKIILPFTNQQRYLGSLQQGNVNLQNSNLRNINMANQRHYNIQQQNSYKNMLQRSLISQHHHSQMPNRVNKINFQHDQSRFPGDGHPGAKRFLTKPGQSDIQQTSMLRRTHNQASIHMKSQRPPPYSSYLQQIEDGTTFKKAKKLKIGKNMRILPWSSFIDPYYKGYETSASDDSDELDSEEEKEITDKYYTRKAGPSVELPVERTDSPDTSRHMTYL
Length419
PositionMiddle
OrganismStrongyloides stercoralis (Threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.07
Grand average of hydropathy-0.910
Instability index60.19
Isoelectric point9.49
Molecular weight48578.94
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04307
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.24|      29|     114|      81|     124|       1
---------------------------------------------------------------------------
   51-   79 (47.53/30.81)	ISKIEIEIIKKLKS.TPCIEKTQKKIKKMK
   89-  118 (42.71/27.58)	ILKTEAGLIRIFGSvTNSLNIAQKKLCELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     139.54|      31|      34|     210|     240|       2
---------------------------------------------------------------------------
  167-  196 (20.61/10.15)	......GSLKH.SIPLKDiskkCGVENptINMLHNVK
  210-  240 (53.42/38.89)	NQQRYLGSLQQGNVNLQN....SNLRN..INMANQRH
  245-  277 (41.48/28.44)	QQNSYKNMLQRSLISQHH...hSQMPN.rVNKINFQH
  289-  309 (24.03/13.15)	GAKRFLTKPGQSDIQ.QT....SMLR...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.73|      11|      35|       4|      14|       3
---------------------------------------------------------------------------
    4-   14 (19.24/13.99)	EESLKKD...LVND
   37-   50 (14.49/ 8.75)	EESKRENfkcLVND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.76|      18|      28|     320|     337|       5
---------------------------------------------------------------------------
  320-  337 (34.09/22.48)	KSQRPPPYSSYLQQIEDG
  350-  367 (35.67/23.84)	KNMRILPWSSFIDPYYKG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04307 with Med4 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LQNSNLRNINMANQRHYNIQQQNSYKNMLQRSLISQHHHSQMPNRVNKINFQHDQSRFPGDGHPGAKRFLTKPGQSDIQQTSMLRRTHNQASIHMKSQRPPPYSSYLQQIE
2) SASDDSDELDSEEEKEITDKYYTRKAGPSVELPVERTDSPDTSRHMTYL
225
371
335
419

Molecular Recognition Features

MoRF SequenceStartStop
1) DSEEEKEITDKYYTRKAGPSVELPVERT
2) DTSRHMTYL
3) FIDPYYKGYET
4) KRFLTK
380
411
360
291
407
419
370
296