<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04303

Description Uncharacterized protein
SequenceMALIAALKNEDIIKKDGEKLRDISPCFSECERLFHIIYKYLTTTSLAHLFNESRDFNNRNQKLTIIECYRFLENMSDNDKRGLALKFCIENLQMCEEVKAKQYEFEEMLTFIINKLYTNQLLHHFHCFELHVLNTDYKLKIPVNKKKFTFMKENIHLLDYKEKRNIMKSLLVEKFEHIPMHLTEVQRLHVLPIEEFILEIIDRENNYIPPLFTITEVFRLTLTSTAYLFPRVSKKLVNMMSSFRPLAEMITPIGRPWLFPIVSHIGYNSYNNTWKLTDGPINKILSKAHLPYSTEYMTSQSYFLYIILKQPRGNVMMKTILGKTNSLGPNNKLNITELLNLFILEAMYECEITSLPTHHPAVQYTWLNLQHLSEFCLFHNNVYFLDLLKLLKKSLIEFKYRKAKDELMWLFLQHVTISVGKFQRECMVEIAEIYKILYTGNEAWVGSSLDVMKMIKFFAPAAIWLCYEKDNKEEFPKPSFIIKNHMELFKKEAKKGSELHDGMLIVIGNAISTDKVNFQEKFFKVLMKQLQGNEDEDKWLLPYGRKVDKRLKAIELTSLDCFTFHAKDMTVKHLMYLFGPSSPVLYTISPAIIESLIRIILSVEVFDLTKLQFLNMLGYYIKNDNLDLTYVIAEAICFRIIDVHMHYSQRITVIRGVLEGLKRLTSHDSSNNLYNILEQLFIRSFMWYNQNDMCQLLIKSLNDKSIGINSHICLPVSQFTGNMEDFSMLISPEIVKMLYFIFMKNTKLTGIDIPIEITRTINENYKFSPKIMKYFSNNPDDYIPPMIIEKNNSDLLIELVANDPFVKEIKFPEEYLSRSKDRYILFCIIFKFLEDNPKVDFNGCFYKILLHFNPKELTLSCNIFIEYLNHRFKNIENEECEKLIKIVNDMIFKYQVITFDKFLLSLIMHPNTDEDIVISLDILFYLLSTCNELQHNLNACLSFIPRREFVCRADSEKFFKKMSLYHKNFPEYTYRELLQKLEKKEDFTIPELHLPIYYKNLAELIIPTVDMMFTNAILLNYNLERFVVILKTFSPIYAYHPSPLSFVYETLFLLNCDNINDPILFQLFTKKIISISESVKSFSADFYQNDVFYYPSIHATCTEVVGKLVEACNIKLIPPKHVARDWRFSEFPPAGQALYTGAIELMFCNYPPNIVAECLLNIAIPRTGENYHEKINAACSLLTVLPMKYQDHIFNFMKYAITSKELVCCKNPKLIFTKIEDIIFHCHDIDSIPHLAVIQTFWQLSSMAMYTKGIEFFEEILVDLVTNESQLLYAARIILPFIVKMSEARDKFKKDETTKCTIALYEMIGKICSNTENQIVYKSLICDIMYFIKYMFIGDVVKEKAEDVIKKMPSDMQELMKFYNSTGSNLEGNRKLSNTNISLLSNQSRLLQRVPAPLDFEEISNNQDNVINNHYDMLNTIQINRNVNQQVQSEYDNILTKSDSIENRSSHPSEYKGSQLQQYLLNTSVPFQNSNQGNMLNMNQKLPIDGRNDISQISRNDGMPDYMMASQKMPQMGMSSNQGVGGQNPLQGGQNIYSGDPRIQADIRLQQKQAFQHQYNLHQSMQNKQPMSHLPNMNQNTNQPMNPYNNPPSQYSGMMHSQGIPYNQHMPGKQSQMQPPPGMGSNFNMPQGMNPYNNPQQFPNMMHHSNMVMHQGVQSHHNISQQGISPIYPQPHMYQGIPNQQQFPSNLQGHGYNQQRINSNLIYCDFEDDDLCGWIGLKNHWKVTQNVDLDAIHSINTSPTGVGNFIYIQKDPSVDEPGYLISPEIFSTQSSYIKIQFYYRKNTISPIMDICVTKGDITKLRCLESISDKGQQQWIFKNIRIPNQMEPFKVVFRVRNMKTIMDVVAIDQISIESIPIIKNGQKGIKAQKNNDIENELAINSKEVENLDKNNETEVEEKSNNYIKKSTKISFHPNFNVGEFPSFAQGVDIFRPSLTNYGCSAIRCSFMKNNCLWSLDNGWKRIDGNLAIEKIGKENITSGLFLVPLASFFEFDLWMSTTATISVIQTYDNHNEKLFTQKGLTSNGWHRFRIPLQAGFVPSSVSIEAIINKNDFVTISNVKLVDSNGEEISCETIQTEPPQKILVQQIINKKQLHNNDNDNIIQRDQPMLARLNGMPVILPTPITMTPIKPLKYDNLERLTSLQQKNLLYNKNTKIFKPRIYPLSLKSSNDQPKNGFSNLIDINSQQISNEWKQKIVNSIIPNNNKDISDQKINNNNQELSIGKILSSIGGQPLLENQLKNLAQRFGFTGITDPRAIELFQKFVNNPIMNQRMSELINSEISKTKINNNLVNVKTGVSPIIPVNVNKNDFEKVFKEQLMNENIKDIQKNQGINDDIIKKFAKIIQLPASDKNDQQPLTRNNLDFVVHNALSHSENNF
Length2378
PositionTail
OrganismStrongyloides stercoralis (Threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.10
Grand average of hydropathy-0.310
Instability index46.46
Isoelectric point7.30
Molecular weight275816.34
Publications









Function






Annotated function


GO - Cellular Component
membrane	GO:0016020	IEA:InterPro
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04303
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     268.47|      42|      45|    1559|    1600|       1
---------------------------------------------------------------------------
 1428- 1457 (28.16/ 9.04)	........NQQV.QSEYDNILTK.SDSI..E...N.RSSHPSEYKG..................
 1502- 1557 (44.67/18.94)	.GMPDYMMASQK.M...PQMGMS.SNQG..VggqNPLQGGQNIYSGdpriqadirlqqkqaFQH
 1559- 1600 (89.30/45.71)	YNLHQSMQNKQP.MSHLPNMNQN.TNQP..M...NPYNNPPSQYSG...............MMH
 1606- 1647 (70.16/34.23)	YNQH..MPGKQSqMQPPPGMGSN.FNMPqgM...NPYNN.PQQFPN...............MMH
 1661- 1690 (36.19/13.86)	HNISQ..QGISP.IYPQPHMYQGiPNQQ..Q...FPSN..........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.21|      36|      40|     773|     812|       2
---------------------------------------------------------------------------
  719-  754 (59.76/32.07)	FTGNMEDF..SMLISPEIVKMLYFIFMKNTKLTGIDIP
  775-  812 (57.45/43.58)	FSNNPDDYipPMIIEKNNSDLLIELVANDPFVKEIKFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     194.51|      42|      42|    2132|    2173|       3
---------------------------------------------------------------------------
 2137- 2179 (65.14/34.88)	NLERLTSLQQKNLLYNKNTKIFKPRIYPLSLKSSNDQPKNgFS
 2180- 2212 (48.00/23.58)	NLIDINSQQISN...EWKQKIVN.SIIPNNNKDISDQ......
 2287- 2316 (39.52/17.99)	.........INNNLVNVKTGV.SP.IIPVNVNK.NDFEKV.FK
 2323- 2355 (41.86/19.53)	NIKDI...QKNQGINDDIIKKF.AKIIQLPASDKNDQ......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.37|      39|      43|     608|     649|       6
---------------------------------------------------------------------------
  608-  649 (63.26/42.59)	LTKLQ.FLNMLGYYIKNDNLDLTYVIAEAICFRiidVHMHYSQ
  651-  690 (61.11/34.26)	ITVIRgVLEGLKRLTSHDSSNNLYNILEQLFIR...SFMWYNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.42|      21|      44|    1972|    1992|       7
---------------------------------------------------------------------------
 1972- 1992 (37.25/27.43)	EKI.GKENITS.GL..FLVPLASFF
 2015- 2039 (26.17/16.63)	EKLfTQKGLTSnGWhrFRIPLQAGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.46|      26|      45|    1251|    1277|       8
---------------------------------------------------------------------------
 1251- 1277 (39.03/26.97)	TK.GIEFFEEIlVDLVTN.ESQLLYAARI
 1298- 1325 (36.43/20.45)	TKcTIALYEMI.GKICSNtENQIVYKSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.53|      17|      43|     929|     945|       9
---------------------------------------------------------------------------
  929-  945 (33.79/18.65)	TCNELQHNL.NAC.LSFIP
 1100- 1118 (22.73/10.29)	TCTEVVGKLvEACnIKLIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.29|      26|      43|    1694|    1719|      10
---------------------------------------------------------------------------
 1694- 1719 (51.02/28.68)	HGYNQQRIN..............SNLIYCDFEDD.DLCGWI
 1724- 1764 (35.26/17.49)	HWKVTQNVDldaihsintsptgvGNFIYIQKDPSvDEPGYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.33|      21|      45|     512|     532|      12
---------------------------------------------------------------------------
  293-  313 (37.88/24.59)	STEYMTSQSYFLYIILKQPRG
  512-  532 (36.44/23.35)	STDKVNFQEKFFKVLMKQLQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.01|      31|      46|    1015|    1048|      14
---------------------------------------------------------------------------
 1015- 1048 (47.11/33.47)	NAILLNYNLERFVVI...LKTFSPIYaYHPSplSFVY
 1061- 1094 (48.90/24.88)	DPILFQLFTKKIISIsesVKSFSADF.YQND..VFYY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.30|      23|      49|    1807|    1829|      15
---------------------------------------------------------------------------
 1807- 1829 (43.17/31.36)	LESIS.DKGQQQWI..FKNIRIPNQM
 1855- 1880 (31.13/19.85)	IESIPiIKNGQKGIkaQKNNDIENEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.74|      55|     817|      15|      72|      16
---------------------------------------------------------------------------
   15-   72 (93.33/61.21)	KDGEKLrDISPCFSECerLFHIIYKYLTTTS......LAHLF....NES.....RDFNNRNQKLTIIECYRFL
  834-  903 (80.41/43.65)	EDNPKV.DFNGCFYKI..LLHFNPKELTLSCnifieyLNHRFknieNEEcekliKIVNDMIFKYQVITFDKFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.35|      25|      49|    1139|    1166|      23
---------------------------------------------------------------------------
 1139- 1166 (36.68/29.42)	YTGAIeLMFCNYPpnIVAECLLNIAIPR
 1189- 1213 (44.68/24.30)	YQDHI.FNFMKYA..ITSKELVCCKNPK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04303 with Med23 domain of Kingdom Metazoa
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