<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04250

Description "Bm2382, isoform d"
SequenceMQQQHPAAASNSGLSVAVPTVEPTTVTVVDRLKHQLLQAYDNGDTKQATDVIIKLEKSNLTKELLEMTRVGAVVNDIRKKVAQSAPELSKRCRTLIKCWQKLAEPKPTSSGSSSANGTPSYASPAVKKGLTPGTPARGPRVISGGSPRLTPAEKSRFTALPSSVPTPSESSGSWNTDASPTFSNGRTVTPYQRSEQKMSANIVANTWKSHAVSADLTIKAVENSLLSDDRVIRNGKRKGGDIATSDIGATNGLSATKRLHYTSASVSPTAPHQSLLAARRADVKSTSELVAQLTENLPGYLTINISQNHRLTGSEHGDNEGQANMDTGHISRTPILFIQTEASKKKEKRGRSKKNKEKEGRIKDQFVANEKVIAVDNEKASTSAMGNADSVPVFNVANSVPSTDKMVVPTRNGKYDWYAMLPSLETLRNREHFRSKPSSNQRKSYIVNVLGREVLALPYIDVGLPDFLEYQYPKPERFYAEENFMYGASRPN
Length492
PositionUnknown
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.05
Grand average of hydropathy-0.621
Instability index42.35
Isoelectric point9.68
Molecular weight53587.68
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04250
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.64|      34|      55|     107|     143|       1
---------------------------------------------------------------------------
  107-  143 (53.01/35.19)	PTSSGSSSANGTPsyASPAVKKGLTPgTP.ARGPRVIS
  165-  199 (60.63/30.30)	PTPSESSGSWNTD..ASPTFSNGRTV.TPyQRSEQKMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.36|      30|      49|     201|     230|       2
---------------------------------------------------------------------------
  201-  230 (49.65/29.02)	NIVANTWKSHAVSADLTIKAVENSLLSDDR
  251-  280 (50.71/29.78)	NGLSATKRLHYTSASVSPTAPHQSLLAARR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04250 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AEPKPTSSGSSSANGTPSYASPAVKKGLTPGTPARGPRVISGGSPRLTPAEKSRFTALPSSVPTPSESSGSWNTDASPTFSNGRTVTPYQRSEQKMSANIVA
2) NISQNHRLTGSEHGDNEGQANMDTGHISRTPILFIQTEASKKKEKRGRSKKNKEKEGRIK
103
304
204
363










Molecular Recognition Features






MoRF SequenceStartStop




1) YDWYAM
415
420