<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04241

Description Uncharacterized protein
SequenceMRQFPQQHQQQQPPPQIRKGPPDVTIEERRIALAQIVNTLRLLPVPQASQQDFVNKAAYQYENTLFQHSQFKVNYLTKLQELLKSLEQKANGIRQSQFSANTNNQIHQQPPLLSHPQQPNFSGPPANPISVNNNNSNITINDGANFVSNSASITPSNNGPSSNINFGTSTNSVNEELKRQIQRKVMSSPIPPQIIASIPGFPEGISQWSQINDFKAKNLLKPEHIAATKMAFEKTFIYYLRIYEHQKKQMIQRQQTQRQQINISGPGDINTTNNNDLKNNNNSNNNNNNNNPNQHMARNQLNKHIPQNINQLPPQMQQKPQNQTINWNSSSIHTRPSVNQPNTSLENYAQVLNTHNIQQVNQAGQTDRPSQANRSSITNQSSQQNHSTVDSVNKTPSSFTQQDIMKLRELKAEADKKPIPLRDITSTLSQSDKEQITTLLKPIAVSFSRVDQSIFLFFQHTRNEKNSIRFFQLKAMFKQLWDGINKGKFMVTVPLAGKIRAEFGQYFSFVNRLGLQAQANRSQGGEAEALQNDPRGANNILQTQQSQNIRTQNKLSTSPGMQQQPAFSQNTVSPLQNQQHHQQNLPQNIQLQTQQVAQSRAQVYKTQSTQAQNSKQVEDSQSQAQSQTQLTQKFQNQQLQQAHQVQPIPSVQQRRQSAQPQAHKKAQPDALQETQEQKQQQGAFWAQKAPQAAQNDPKARENTQKATQPLKVIKNTQSQKNKQSPKIGQSQEKKIQQQPPQAQKDTGLTSKSNPDTSQIKNSTIAGVPTYGKPGIAADQIKLPTRKRKASAASTHSLGSSTASPEELRLNTNQSIKKGKVDESEAAKIKEIALKLQRKKEESKQNPLGYFISSLGEALSIPPEKIEQAKKIGEVEKADDLTTSPEETGWEASTVPALTLKNAFQSIDVVKTAPRSVPQASVKKLDLNDVENKDVSNPIGGNKMVRALLGEDLLNINAWSYDELVSVLCVDERAMKRDYWTLKC
Length983
PositionTail
OrganismGeotrichum candidum (Oospora lactis) (Dipodascus geotrichum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Dipodascaceae> Geotrichum.
Aromaticity0.05
Grand average of hydropathy-0.947
Instability index54.06
Isoelectric point9.81
Molecular weight110259.84
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04241
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     118.62|      27|      28|     592|     618|       1
---------------------------------------------------------------------------
  307-  349 (26.94/ 6.15)	QNINQLPPQ..MQQKPQNQtinwnsssihTRPSVNQPntslenYA
  350-  372 (29.05/ 7.35)	QVLNTHN....IQQVNQAG..........QTDRPSQ........A
  571-  601 (29.71/ 7.72)	TVSPLQNQQhhQQNLPQ........niqlQTQQVAQS......RA
  602-  628 (32.91/ 9.53)	QVYKTQSTQ..AQNSKQVE........dsQSQ..AQS......QT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.94|      18|      25|     117|     138|       2
---------------------------------------------------------------------------
  117-  137 (26.06/17.85)	QQPNFSGPpaNPISVNNNNsN
  259-  276 (28.89/ 9.22)	QQINISGP..GDINTTNNN.D
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.91|      15|      19|     659|     673|       3
---------------------------------------------------------------------------
  659-  673 (27.28/12.91)	QPQAHKKAQ..PDALQE
  679-  695 (20.14/ 7.15)	QQQGAFWAQkaPQAAQN
  715-  729 (20.49/ 7.43)	NTQSQKNKQ..SPKIGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.03|      14|      49|     777|     798|       4
---------------------------------------------------------------------------
  758-  771 (24.16/ 8.05)	QIK......NSTIAGVPTYG
  779-  798 (15.88/21.34)	QIKlptrkrKASAASTHSLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.29|      47|      90|     807|     858|       5
---------------------------------------------------------------------------
  810-  858 (73.14/56.60)	NTNQSIKKGKVDESEA..AKIKEI..ALKLQRKKEESkqNPLG..YFISS.LGEAL
  864-  891 (24.62/ 9.86)	.........KIE..QA..KKIGEVekADDLTTSPEET.....G..W.......EA.
  901-  952 (59.53/32.85)	NAFQSIDVVKTAPRSVpqASVKKL..DLNDVENKDVS..NPIGgnKMVRAlLGEDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.43|      19|      94|     635|     653|       6
---------------------------------------------------------------------------
    2-   19 (23.94/ 7.04)	..RQFPQQHqQQQPPPQIRK
   32-   50 (27.26/ 9.09)	ALAQIVNTL.RLLPVPQASQ
  635-  653 (33.81/13.14)	QNQQLQQAH.QVQPIPSVQQ
  731-  744 (26.42/ 8.57)	QEKKIQQ.....QP.PQAQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.10|      40|     238|     138|     197|       7
---------------------------------------------------------------------------
  149-  197 (53.17/56.50)	NSASITpsNNgpSSNINFGTsTNSVNE..............ELKRQIQRKvmssPIPPQIIAS
  373-  426 (61.93/23.51)	NRSSIT..NQ..SSQQNHST.VDSVNKtpssftqqdimklrELKAEADKK....PIPLRDITS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04241 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ANGIRQSQFSANTNNQIHQQPPLLSHPQQPNFSGPPANPISVNNNN
2) KQMIQRQQTQRQQINISGPGDINTTNNNDLKNNNNSNNNNNNNNPNQHMARNQLNKHIPQNINQLPPQMQQKPQNQTINWNSSSIHTRPSVNQPNTSLENYAQVLNTHNIQQVNQAGQTDRPSQANRSSITNQSSQQNHSTVDSVNKTPSS
3) NRSQGGEAEALQNDPRGANNILQTQQSQNIRTQNKLSTSPGMQQQPAFSQNTVSPLQNQQHHQQNLPQNIQLQTQQVAQSRAQVYKTQSTQAQNSKQVEDSQSQAQSQTQLTQKFQNQQLQQAHQVQPIPSVQQRRQSAQPQAHKKAQPDALQETQEQKQQQGAFWAQKAPQAAQNDPKARENTQKATQPLKVIKNTQSQKNKQSPKIGQSQEKKIQQQPPQAQKDTGLTSKSNPDTSQIKNSTIAGVPTYGKPGIAADQIKLPTRKRKASAASTHSLGSSTASPEELRLNTNQSIKKGKVDE
4) NSASITPSNNGPSSNINFGTSTNSVNEELKRQIQRKVM
90
248
520
149
135
398
822
186










Molecular Recognition Features






MoRF SequenceStartStop




1) QIKLPTRK
779
786