<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04230

Description Uncharacterized protein
SequenceMADPSPPREIAPKAPQAAQPDAAGLSVSPPLTAVKSSKSKKDNKTPKKSQADKEKKQAKEKKKLIVACIGCRKKKIKCSSDRPACSNCLRLNIPCEYPVIRNRGSRFGYMEMLNRRMQHLEKYINCSSNPQYHPQFVTIHQKSRKTAQSTVAGQLPGSANSGYTNFNSNIASVQEPETLITQLGPQLTKELSPPPASNFSSNHKQNIKLPPLDIILHLVELYFQHVHGQTYSFLHKPSFIPLIKQGKVNRTLLLALCGLTARYSKHPLIASNPPYEAGEHFIADARNSLSEEFDEPTIETIQAVIIIVQHDFFRYKGKRSMIYVSLAIRMAASLELHVESKDPSLSFRERESRRRTYWSLINLDRLGHSGTHWQVHLRTDTLKIQLPCKDYYYENNIPVVVETLDGSLPPPLPGQTNQNIRRGERGLYSYIVETTILWCDINKYAMEEFKTEKIPPWKEGSKYHSLETRLQHLFSSLPKEYQYSKENLNVLCTLNQGAPLIHLHSGLLMSLCYLSRTMFPFNYDKMNFEEQPPAAFIERAAINIVASANSLSSIIEDALSLEDFNLAPFVGFSVFALSSVHIANSFSKDPEVSSAAKNNLAINLKFLVLMREYWYSVGVWCVLLKDRYFEKARRHRIKSSQNYYTQSDLSSKFPNLENKDESSEVFSRPGTPPIAYAPEELIGLATNKGDSEEHTPPKSFESPSHSSHYDREPGRDEVNPTTVETPQHISSTWEKAVSRSYPNQVEGAESAQSLKRDLNQNTFSRKRPRTLRDQNQNMALPQQQQHYQNINKFGNYSRQTFSQLDNMLDDSIFPNKEATVMKQQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQQQIPHRSSRESTATSMETAGSIPAGPTGRDQNINGGPTSPALLKNRNALENYASGNKSMNALLQDTSGEWLNSLELTDFTRFANEDRSLIDLNNPTYWFDTEMKVQLEERQRGHMDMPIEDLGMPSTGNNSTFTKNTNRNGNTTNSNMGPDSSSNKNHNNKTSNDDTEDNNNNTSSSNIGNKYGLNPPGKMRQMIIPLQNETEPKDLRVVDESLFHQSLIHQPFTPSDMGAVGDSAVSISMGHSPGRGGKPNSDRLDKTAVATDYHAQTPSSLTSSSVFESDHDTAFVAASHPKQHQPSQPSSTLQQEPQVPKTDSMLLDEIFQQVGLETSIDPFINSDDD
Length1206
PositionTail
OrganismGeotrichum candidum (Oospora lactis) (Dipodascus geotrichum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Dipodascaceae> Geotrichum.
Aromaticity0.07
Grand average of hydropathy-0.804
Instability index58.57
Isoelectric point7.24
Molecular weight136220.54
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04230
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.35|      15|      15|     826|     840|       1
---------------------------------------------------------------------------
  826-  840 (34.18/14.11)	QQQQQQQQQQQQQQQ
  842-  856 (34.18/14.11)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.08|      29|      29|     986|    1014|       2
---------------------------------------------------------------------------
  986- 1014 (53.71/30.39)	DLGMPSTGNNSTFTKNT.NRNGNTTNSNMG
 1016- 1045 (47.37/25.92)	DSSSNKNHNNKTSNDDTeDNNNNTSSSNIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      14|      31|     313|     326|       3
---------------------------------------------------------------------------
  313-  326 (25.78/16.40)	FRYKGKRSMIYVSL
  347-  360 (27.02/17.52)	FRERESRRRTYWSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.02|      17|      31|     658|     679|       4
---------------------------------------------------------------------------
  658-  679 (26.79/22.73)	NKDESSEvfsrpGTPPIAY.APE
  687-  704 (28.23/12.63)	NKGDSEE.....HTPPKSFeSPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.47|      23|      29|    1118|    1141|       5
---------------------------------------------------------------------------
 1118- 1141 (35.38/28.32)	SDRlDKTAVATDYHAQTPSSLTSS
 1146- 1168 (43.09/29.94)	SDH.DTAFVAASHPKQHQPSQPSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.41|      31|      31|     752|     782|       7
---------------------------------------------------------------------------
  752-  782 (52.21/29.86)	QSLKRDLNQ.NTFSRKRPRTLRDQNQNMALPQ
  784-  815 (50.19/28.42)	QQHYQNINKfGNYSRQTFSQLDNMLDDSIFPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.70|      28|      31|     908|     937|       8
---------------------------------------------------------------------------
  908-  937 (41.43/27.26)	LKNRNALENYASGNKSMNALLQDTSgeWLN
  938-  965 (48.27/26.06)	SLELTDFTRFANEDRSLIDLNNPTY..WFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.89|      29|      34|     524|     556|       9
---------------------------------------------------------------------------
  524-  552 (49.42/36.55)	DKMNFEEQPPAAFIERA..AINIVASANSLS
  557-  587 (44.47/23.15)	DALSLEDFNLAPFVGFSvfALSSVHIANSFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.25|      17|      34|     154|     183|      10
---------------------------------------------------------------------------
  154-  170 (32.07/ 7.52)	QL.....PGSANSGYTNFNSNI
  186-  207 (27.18/21.47)	QLtkelsPPPASNFSSNHKQNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.09|      12|      17|      67|      78|      11
---------------------------------------------------------------------------
   67-   78 (24.17/15.78)	ACIGCRKKKIKC
   84-   95 (24.92/16.49)	ACSNCLRLNIPC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04230 with Med2 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) APEELIGLATNKGDSEEHTPPKSFESPSHSSHYDREPGRDEVNPTTVETPQHISSTWEKAVSRSYPNQVEGAESAQSLKRDLNQNTFSRKRPRTLRDQNQNMALPQQQQHYQNINKFGNYSRQTFSQLDNMLDDSIFPNKEATVMKQQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQQQIPHRSSRESTATSMETAGSIPAGPTGRDQNINGGPTSPALLKNRNALENYASGNKSMNALLQDTSGEWLNSLELTDFTRFANEDRS
2) IDLNNPTYWFDTEMKVQLEERQRGHMDMPIEDLGMPSTGNNSTFTKNTNRNGNTTNSNMGPDSSSNKNHNNKTSNDDTEDNNNNTSSSNIGNKYGLNPPGKMRQMIIPLQNETEPKDLRVVDESLFHQSLIHQPFTPSDMGAVGDSAVSISMGHSPGRGGKPNSDRLDKTAVATDYHAQTPSSLTSSSVFESDHDTAFVAASHPKQHQPSQPSSTLQQEPQVPKTDSMLLD
3) MADPSPPREIAPKAPQAAQPDAAGLSVSPPLTAVKSSKSKKDNKTPKKSQADKEKKQ
677
955
1
953
1185
57

Molecular Recognition Features

MoRF SequenceStartStop
1) MADPSPPREIAPKAPQAAQPDAAGLSV
2) MLLDEIFQQVGLETSIDPFINSDD
1
1182
27
1205