<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04226

Description Uncharacterized protein
SequenceMSSSRMNASNHGLYGDNHHGANNNNNHHHSNNTNKSRFNMMSSISQRNGSSLQSRSISSARDDLAIHRYMLTHPEGVAPLLEDKNSASEYIYPDFFPWKKTKEEDVLTTQNLQKGYNPLTTVTSETSTARNPMMQAFRQRSSLYALSYFMLNAMDVKEKSSRITSNSTFKPPPRVTLTEQKKEAWLRDLADPSVPLRRLSRTIPHGTRNRSLLEQCCNKNIPIARAVWFARCVGANELRGLKRKGSTQVGSVTEVQWIFEWTEQVTEFIEKVIKECPEESSATSASANIAAAASSNNPTGSSGTHPSTVSSKSSPSTPLASASALTSLNNNSPSASSPLSSIPAKLPMKPAPKPFGSASSASTKSTLSNSQPWKVKMEYITRLAANLFSEGLLDKPLFLKWCIVNLQKCRIEELPVAILFIRLFWDGIVQSRLLSQNLALALLERFSELSSPTFSKYQVFVTFKEKVSEALFNFFIFSPDSFVIPQYWKKLGPVLIEALKGINDEVAQQVLELVCMRNESFSVTDVSATRASRNPQYIIIDSLDKANVPYNWSSLIQSINVNKIPEQDALMVAFEWATSKNRAGIDRVYICASMLTEWHNVLKWDISAGFLNFLDSITCADGYDMKNLYDMVSELQDRDWFSAGSFFRRLISQGTLFISKQQPSMNVKIKILANLPVQYSTGLRNQQIMMLRNLKVNTDEDHNSLLEAKSILSTKLSFLFAEKYYFDQYELFEEHTTILSNLSKVNKMVLSTWITESLNSKLSTEFELSVSQFAVLQNVFEILRDFKALYVMIERVTTTTTNGSLLYFMANSIRDHLSIFAAIADVVQLIQLFVNQYKSLNVKTKMSKGLWDLVIFALKEVPESNIQLRTELEQIVTPTGQTPLKDITTLSPMSDIVSESIVANQELSEFLQERLGTHDAIDNRSLPKFFESISEMFLNACKQEDHNSEEIRKVVVLLQHLKDTDPGIFSELAIKWIKEKVEPEFCYDSNSFTRILLFLVIYECVTLEKIAETFLQMVKVKVPGSTQSTKVILSLISEDYISGIQLKASEKLALNMQRHHFAKDHGIIYLKYILQEVLDSTEMTSLSSSISTSVSQFLLWFLTHDLNQFISQMVDPILHSGNTHAINELRLILLKLLKIDNNSTANHFSNAKVEILHILEIFNPLNLALCQVYVRVVLIFQREQQTHTEIAPISTGHATPVVPVNNENILGVLMEVIASAHVRKLSERALGDLMVRLPEEVKSQLLMKCELLFIQSPQFPCIVNIETGTGNIINYVLEVVDAIATSASIDLFESHSFEVTEALDKLLSACDLFTQKHQQEKDVMQTEKIDVPTSSGENPQLYGNEDLLNDEASVKGAILLFVKILVIYSPKILSWAENIRDKVTNGIIRLLSTQFVVSRVDLYNLLTDTLESIKRHMKRPDRGDGASLPGSDTMQKQVSSVPLSSAGMMNTSVASTELLINDSPVSRPNLGGNTTPASVLTDIPPAVLANSKFAPTAAAILNHSSSNDISDNSSSSPGIRNVNSLTAAPNPGVVSDESDYLSDLILYNKTTKTYSNLNVRAFDLLEESNHTMQINDVALNLAMFDGFIEKKNPV
Length1594
PositionKinase
OrganismGeotrichum candidum (Oospora lactis) (Dipodascus geotrichum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Dipodascaceae> Geotrichum.
Aromaticity0.08
Grand average of hydropathy-0.145
Instability index43.16
Isoelectric point6.06
Molecular weight178416.75
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04226
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     285.21|     106|     279|     322|     460|       1
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  322-  411 (133.26/105.78)	..............................ASALTSLNNN...SPSAS..SPLSS.IPAK..LPMK...............PAPKPFGSASSASTkSTLSNSQP.WKVKMEYITRLAANlFSEGLLDKP.LFLKWCIVN........LQKCRI
  565-  711 (120.65/89.93)	PEQD...ALMVAFewatskNRAGIdRVYicASMLTEWHNVlkwDISAGflNFLDS.ITCAdgYDMKnlydmvselqdrdwfSAGSFFRRLISQGT.LFISKQQPsMNVKIKILANLPVQ.YSTGLRNQQiMMLRNLKVNtdedhnslLEAKSI
  712-  761 (31.29/11.04)	LSTKlsfLFAEKY......YFDQY.ELF..EEHTTILSNL...SKVNK..MVLSTwITES..LNSK.......................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     520.59|     140|     325|     762|     909|       2
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  762-  902 (217.71/147.98)	LSTEFELSVSQFAVLQNV.FEILRDFKALYVMIER....V....TTTTTNG......SLLYFMANSIRDHLSIFAAIADVVQLIQLFVNQyKSLNVKTKMSKGLWD.....LVIFALKEVPESNIQLRTELEQIVT..PTGQTPLKDITTLSPMSDIVSESIV
 1086- 1222 (166.10/105.90)	LSSSISTSVSQF.LLWFL.THDLNQFISQ..MVDP....IlhsgNTHAINElrlillKLLKIDNNSTANHFS..NAKVEILHILEIF....NPLNL......ALCQvyvrvVLIF.QRE.....QQTHTEIAPISTghATPVVPVNNENILGVLMEVIASAHV
 1227- 1339 (136.78/94.71)	...ERALGDLMVRLPEEVkSQLLMKCELLFIQSPQfpciV....NIETGTG......NIINYV.......LEVVDAIATSAS.IDLFESH..SFEVTEALDKLLSA.....CDLFTQKHQQEKDV.MQTEKIDVPT..SSGENP...................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04226 with Med12 domain of Kingdom Fungi
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