<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04192

Description Uncharacterized protein
SequenceMPTPRYPPAGLRAAHPSLGNKAPHKRRASGQPTADVSLADPVPIEEFPPPAWRTVLNSRADLGYPDFYPSRPGFGQPEDEMSDTFVKSGFSLKPAVNVTAESFSMHGPVYQQLQTGGLERLMELGREIIAQRNAAMPSFQERAFRIPVRVTYNDTKRSQFIADLANPAIPVTRLMRNPVPHGFKGVELLETMFHPPQPGMRPGTVSAAGKPPPEPIPIDRALWFIRILGANEISAHRGRAQPVSSVQAPSPAAATPSSTATSAPVPLPLNSNDWYTAEFTTAFTAWLRMQLAQLVLPTKPKAGGGGGTLPPPKTPTGVLGDEKSRTRWLAKWQYSNTLLKQLNRKRLISQRQLVGWLADFLGQANLAQVGFVAQLIHENLNDVAESSSISRHCVRSACVKLKEIRGSPAKETMTKVDEQLTTIIRVLYETDPEVMLSPTTWVRFSPLVGSIVDSVTPLWADLERRNNALMFKPIVVDPGASPRRQQMAEIHMLDSICAETDMSALCKAYFSGPCAPTSPKIDVSKLEEKVFILVNWAMGLYHMGVHRPYAVYTMLKKWQQWHEEIRPNDHFDFFPILYKWLDTSVPARKAENVLPIGISFGELTRQGLFSYGRYLNTLISHGHSARFSKGKGPPSHHLELLRVMPIFVEAPDLLEQRRLVLSGDGENREREQAEEDHQLETFRQEMKEYVPEVFGLRRYGKSAFIRESIDYQIPMAAGITRFEFVHSRFWLFAAAVHHFKRQGSQPPMDASTYARVMNVFMQCRGYSTLADFLVKGITGTEDPEILLIILDSIKRDADVWTSIDRWNQITAALVARFRAMQRRGEFCAPLVAVLQMLVQHHRLVDPHAEAEVLKARERHRRVSPEAPSIAVDMDQSMEGLRQVITAGNTEKAVGLAPKMFTRHGKFDLWSTTWWQNVIQAVQAGEAGKPNAVNAAVAHITEVIDQAGDGSLRPVFVTWVASLTPSTRVDLFGRRSVPPVVRMLLVLIVRRLLGSHTLLEQVLFPELKHAASLVSASHPRLSSKRTYAVEWAVTLAQQLLLCTPHKSLPPASLREAYVVQTARAAAFHASNVPNLIQHLPVLVVLERSKLVPEKTRNQIGVIFRGLAELPQFKTAAFRNLDVLKDAFLSNDWIKRSNDSSLETGMVEGLKLMMSDKRSKSSESLPTLEGGGKYSAWRYTRIVLEMRVEFKRLTMRIANNEEPHEARKQLSQIVKQSLDREATPDDTDLLVEAFRGADSVVAQEILAVGLERLGDLLRRLLGAEDQHQVEQTSSGIDLVLRVISSIGRQDRLEAAAAAARDRLFNLLADAFQSLERHVSNEDDVHMLPGATPPEPGTILKAVLNLLRFVLSIPSTEIHIPSSPKPDFGALVVAFLHLAVALCSRSQGYTNMESMRDLLIFLVDSVPANSQAAVYHARVFEASTPAVQDLLARSPSFASALPRPKTDYRAMSMCSSSGLVDSDMGMALEDRPWEMVEQMVDQPILKHCDMFLTSKALKDTSSIPIALFKPQLVRDEVPDAAREGEHPWEYASSERNLGNGFGGEPIAARQAATILYARKDGNVGDQPTLVMPPTPAKVKRLNPRNSTPVKGAGTNNDPISIESDESEEEEEEPRPASKRPRTGSKTSTGSTRQVTGGKAPRKAAPARKAPAKNVRSTSGKEVKGRRKSGQEQ
Length1669
PositionKinase
OrganismCutaneotrichosporon oleaginosum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Trichosporonales> Trichosporonaceae> Cutaneotrichosporon.
Aromaticity0.07
Grand average of hydropathy-0.294
Instability index47.21
Isoelectric point9.14
Molecular weight185203.08
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04192
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     184.67|      57|      93|     931|     988|       1
---------------------------------------------------------------------------
  931-  988 (88.36/58.01)	AVNAAVAHITEVIDQAGDGSLRPVFVTwVASLTPSTRVDLFGRRSVPPVVRMLLVLIV
 1027- 1083 (96.31/57.86)	AVEWAVTLAQQLLLCTPHKSLPPASLR.EAYVVQTARAAAFHASNVPNLIQHLPVLVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.21|      38|     138|    1398|    1469|       5
---------------------------------------------------------------------------
 1398- 1442 (49.09/85.68)	FLVDSVpaNSQAAVYHARVFeASTPAVQDllarSPSFASALPRPK
 1471- 1508 (66.12/29.11)	EMVEQM..VDQPILKHCDMF.LTSKALKD....TSSIPIALFKPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.14|      50|     114|     596|     649|       6
---------------------------------------------------------------------------
  596-  649 (77.92/56.82)	IGISFGeLTRQGLFSYGR....Y...................LNTLISHgHSARfsKGKGPPSHHLELLRVMPIFVE
  690-  762 (75.22/41.26)	VPEVFG.LRRYGKSAFIResidYqipmaagitrfefvhsrfwLFAAAVH.HFKR..QGSQPPMDASTYARVMNVFMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.25|      37|     261|     874|     912|       7
---------------------------------------------------------------------------
  874-  912 (56.78/48.16)	DQSM.....EGLRQVITAGNTEKAVGLaPKMfTRHGKFDLWSTT
 1137- 1178 (58.47/39.25)	DSSLetgmvEGLKLMMSDKRSKSSESL.PTL.EGGGKYSAWRYT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.96|      19|      93|     708|     728|       9
---------------------------------------------------------------------------
  708-  728 (26.48/20.38)	SID..yQIpMAAGITRFEFVHSR
  802-  823 (28.49/16.21)	SIDrwnQI.TAALVARFRAMQRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.55|      20|     537|     278|     297|      20
---------------------------------------------------------------------------
  278-  297 (36.82/20.27)	EFTTAFTAWLRM..QLAQLVLP
  825-  846 (33.73/18.01)	EFCAPLVAVLQMlvQHHRLVDP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04192 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ARQAATILYARKDGNVGDQPTLVMPPTPAKVKRLNPRNSTPVKGAGTNNDPISIESDESEEEEEEPRPASKRPRTGSKTSTGSTRQVTGGKAPRKAAPARKAPAKNVRSTSGKEVKGRRKSGQEQ
2) GRAQPVSSVQAPSPAAATPSSTATSAPVPL
3) MPTPRYPPAGLRAAHPSLGNKAPHKRRASGQPTADVSLADPVP
4) RDEVPDAAREGEHPWEYASSERNLGNGFGGE
1545
238
1
1511
1669
267
43
1541










Molecular Recognition Features






MoRF SequenceStartStop




1) QVTGGKAPRKAAPARKAPAKNVRSTSGKEVKGRRKS
2) YPPAGLRAAHPSLGNKAPHKRRAS
1630
6
1665
29