<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04185
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSHGQHLPSPAPTPFPGAPPDDPTIRATLEKELQRLAQDLYEMEVCAGEVVAGMEGQVAERLEKVNRALVELTRLAPQVTDSVPKQVIENVDKARNPHQYTKTSLSRATGENQYALGRLLGLESFRRQLESGLSDAFPDLPLPERRHKPVGVENGEGGFGDGAGTDGEGSRGGAGEKREAGTRGGSEAVSSKLEEGDGESRGLEDGSGAGRPGEGQGAAAAQRAESEVKTEDLAGVSFGTETDVAIGEDGFAGRREMDTRAGAELGESDANGDSKPAV |
Length | 278 |
Position | Middle |
Organism | Cutaneotrichosporon oleaginosum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes>
Trichosporonales> Trichosporonaceae> Cutaneotrichosporon.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.731 |
Instability index | 41.72 |
Isoelectric point | 4.69 |
Molecular weight | 29059.38 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP04185
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 176.01| 43| 43| 155| 197| 1
---------------------------------------------------------------------------
155- 197 (76.31/27.76) GEGGFGDGAGTDGEGSRGGAGEKREAGTRGGSEAVSSKLEEGD
206- 243 (56.78/19.03) .....GSGAGRPGEGQGAAAAQRAESEVKTEDLAGVSFGTETD
247- 275 (42.91/12.82) GEDGF...AGRREMDTRAGA.ELGESDANGDSK..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 73.72| 20| 120| 2| 21| 2
---------------------------------------------------------------------------
2- 21 (41.38/28.06) SHGQHLPSPAPTPFPGAP.PD
124- 144 (32.34/20.20) SFRRQLESGLSDAFPDLPlPE
---------------------------------------------------------------------------
|