<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04180

Description "BMA-DPY-22, isoform b"
SequenceMAMCEQEWVTQRIYRRCEDGALDCFSSHQLRKNCLGQQLLRMALRRRSEREIVRELTICNGNSKKSLIDKLLNVLNIWNTRATYFDFKLMIREISPEGCTSKHAQQGAIAADALLGEIGKCCRDLFTQSHKSDKKLPPAAVGKAFRLKDITAYWLISPLVHACPRPGNLPASFPAITVQGKFLKEAAAMLDTSSDNNKERIQQSTWLLSQEPFLNLVLTCLNGEEQQRDGLVGSMLKQLQELALKAKDNPLLPYLRIFSLEREGVLLRISLVGGMFDSVCHTSICDTWALTLFQLMLYGVISKERDGYLFDSCYDMLSTLLVWSITDPMNAAAMNTQDPDTKFRFPTYSLIVKKLRKELNERALIPELRSLIQFLPIPKPQFELITCEPYGTLPTSPQKLGKSQSQGQIIQTTVKANRHGLQFAEKVKLSAYDIIQYLNIDSTLLKRPWNWSMLQAVKLDRLPVPVQRYIQRLVHHSHYNEFVRPTICGMDRPPNLDIYLSPPMMDVSETPATLHHVSSSAATSTTTSASSTNVPVSSGGAAMDVGATLGPVVQGRAMSYQSSSTPTCTSIPDGSTPSSTPGAPSTAATAMIFPGQSGPMPALPDLTGRGQNNASPRGARGGRRKAAGLSTRSQGTTRKQRQQRQQTVDQLAVAAAAAAAAAQQQQQQMGSAVGCGGGPPQQPTYPSTWATGPQQTGVPQQFASGPSAPPSGTGQAGTAMGTQTTEDSKMKIHSMILQKRQAQAASSATATQQGVTGGPQPSMQDVNAYQISAGPPQYGGNMIMKVETGANSMQMVDHTQQQQQQRQQQQYAQQQQLIQMQQDVQGGSQYVVHQQQRGGIAYGQSVQQATYDSRFNQQQLQYGQQPQQQQQQQYHPTQQY
Length880
PositionKinase
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.06
Grand average of hydropathy-0.467
Instability index52.07
Isoelectric point9.20
Molecular weight96772.89
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04180
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     235.72|      47|      47|     628|     674|       1
---------------------------------------------------------------------------
  577-  626 (53.34/17.46)	PSSTPGAPSTAATAMifPGQSGPM.PALP.DLTGRGQnnAS.PRG..AR........GGRRKA
  648-  696 (66.01/23.29)	VDQLAVAAAAAAAAA..QQQQQQMGSAVGcGGGPPQQ..PTyPST..WA........TGPQQT
  698-  741 (41.99/12.22)	VPQ...QFASGPSAP..PSGTGQAGTAMG......TQ...T.TED..SKmkihsmilQKRQ..
  809-  840 (35.08/ 9.04)	..Q........QYAQ..QQQLIQMQQDVQ..........GG.SQYvvHQ........QQRGGI
  841-  871 (39.30/10.99)	AYGQSVQQATYDSRF..NQQQLQYG.....................qQP........QQQQQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     164.22|      39|      51|     266|     304|       2
---------------------------------------------------------------------------
  228-  261 (38.62/17.64)	..RDGLVGSMLKQLQELALkaKDNPLLPYLR.....IFSLE
  266-  304 (67.67/35.42)	LLRISLVGGMFDSVCHTSI..CDTWALTLFQLMLYGVISKE
  320-  354 (57.92/29.45)	LLVWSITDPMNAAAMNTQD..PD....TKFRFPTYSLIVKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.36|      10|     159|     637|     646|       8
---------------------------------------------------------------------------
  637-  646 (19.48/ 8.49)	TRKQRQQRQQ
  799-  808 (19.88/ 8.82)	TQQQQQQRQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04180 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETPATLHHVSSSAATSTTTSASSTNVPVSSGGAAMDVGATLGPVVQGRAMSYQSSSTPTCTSIPDGSTPSSTPGAPSTAATAMIFPGQSGPMPALPDLTGRGQNNASPRGARGGRRKAAGLSTRSQGTTRKQRQQRQQTVDQLAVAAAAAAAAAQQQQQQMGSAVGCGGGPPQQPTYPSTWATGPQQTGVPQQFASGPSAPPSGTGQAGTAMGTQTTEDSKMKIHSMILQKRQAQAASSATATQQGVTGGPQPSMQDVNAYQISAGPPQYGGNMIMKVETGANSMQMVDHTQQQQQQRQQQQYAQQQQLI
509
818










Molecular Recognition Features






MoRF SequenceStartStop




1) QYHPTQQY
873
880