<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04140

Description Uncharacterized protein
SequenceMSPPRRRSARLASASTPKPKKVSQLSSLTERDETPEEVESTSLDGVVASPHPQPATPASSALKPPMSEMHPSKVHPTATGSSETWLGFRDIKSANVARGKSAMNPQATPSRLSGVPSSSFTFNLTGPAGETGLSTDAQRMMADLREEAAKIKADLVAKRELEKLDEQVNGRKIARAKGKSGRFSAAHMEEFKKMDSIEGHASAFRAQPGRFTPVKKSLKRTSSKANLEDTPKSTLHRSPSKNNLQSTPSQAVSGLKCTSSKANLDEHIEKQPLGTTPSKLRVFAPQPQPSPSPVKRVRQQIEDDASSRRPISRDGSSLPRPTSSSNASASLARSGSTLTSSTSPAKATAARTGLPKISQPALTKSPSKASLSGLTQSTSKTDLGELTKSPSKPALGGTAKPAATHDLATLSRTVELKRRIVSPGRFERVKSILRGGKSPAQPAKSAIPQPFTGVSQTPGPRILDKPLPAVPFTTPRRKLFKRVDFTPDSKDTPSKSRGEVNYPNLDAILSRMNEPESHGAPREIKSPLPASPNKREGQAPEVPTVPGAFTFRSDRTARFGTGSPAGFGSSPGQLSVRQVRASITPVEEMPGSFPETADLPRATHTSKTPVKSMTAGIKHGLTNEKRARTNTEPFVLNKEGSTPAKLVFEGVPHGLPNEKRARTHVEPSHPNKENKSPVKILTGVAHGLANKKRARATEDDEPDVDQEGADRGGKRRKAELAPQPRILGTPKLARSTPIPSPQKVSAGTPSPVCGEIVMRGEDCVSLGWCFWHRACYGCLLCGSKHIASGVKLEELFGDMDDDLEDNMGKTRGREIEEPPLCAHCLVEAELDGMDERAVVQKGLRRMDCVDGGLGRTRWEASQGQPLPLRIGSHQTGAPVPESPAYRSPSLRATGQRSSITNHDRNQQRDAIDAIDPPDSTIYVSINDPLGEPAFKPSPTKPIPRWMQMLLGNRRQYYPDASRQSTPVSPSRVSSTSTQQLGPLPERARTSSSISTVCPQKILNPASTPPSLSPRVSSLTRTSSGGSITDFYRRTVEDHMKRHTPSSWVSHEPLKRPSSRMAYIQGHQRTVTEVSTSSAYATPPEFSFEEHNEIATLPCRPQPGLAGTMPSRHVAFDELPAQLTRTRHPLSAPAVPSSHKHDILTTLIDRMLSRCRRPHLPLRPIIVASRLTARSSIAPLSTIVFHQSRALLVTLATIEAQNHLQRLGTKDHQLPVANKSTAATMAPVENNPQELLEQQLKDTIQDLYQIMLQITMYTTTPTHSSHTALTSSLQTLSASLQAVHTTAVAGAPPTPDGVPPNAQDQLGMPPGVPLHDPARHVTPGALPNIPPELVQYVENGRNPDIYSREFVELVRRGNQLMRGKMGAFAQLRDVLAGEMRSAMPEFPDKFVLFVMATLHVVS
Length1401
PositionMiddle
OrganismVerticillium longisporum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Plectosphaerellaceae> Verticillium.
Aromaticity0.04
Grand average of hydropathy-0.617
Instability index64.16
Isoelectric point9.88
Molecular weight151522.94
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04140
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|    1314.04|     212|     213|     410|     621|       1
---------------------------------------------------------------------------
    3-  210 (175.77/52.68)	................P.P.RRRSARLASA...STPK.PKKVSQL.SSLTERDETPE....EVESTSLDGVVASPHPQPATPASSALKP.PMsEMHPSKVHPT...ATgSSET..........WLG...FRDIKS.ANVA..RGKSAmNPQATPSRLS....GVPSS...SFTFNL.TGPAGE......TglstdaqrmmADL..................................REE..AAKIKADL..............vakrelekldeqvNGR..KIAR..AKGKSGR..FsaahmEEFKKMdsI....EGHASAfrAQPGR
  246-  444 (239.97/74.37)	STPS.QAV.SGLKCT.SSK.ANLDEHIEKQP.LGTTP.SKL..RV..FAPQPQPSPSPVKRVRQQIEDDASSRRPISRDGSSLPRPTSS.SN.ASASLARSGS...TL.TSST..........SPAKAT..AART.GLPK..ISQPA..LTKSPSKASL..SGLTQSTskTDLGEL.TKS.PS......K..........................PALGGTAK........................PA....................athdlatLSRTVELKR..RIVSPGR..F.....ERVKSI..L....RGGKSP..AQPAK
  445-  662 (322.82/102.37)	SAIP.QPF.TGVSQT.PGP.RILDKPLPAVP.FTTPR.RKLFKRV.DFTPDSKDTPSKSRGEVNYPNLDAILSRMNEPESHGAPREIKS.PL.PASPNKREGQ...AP.EVPT..........VPGAFTFRSDRT.ARFG..TGSPA.GFGSSPGQLSV..RQVRASI..TPVEEM.PGSFPE......T..........ADL.............PRATHTSKTP..........VKSM..TAGIKHGL...................tnekrartNTEPFVLNK..EGSTPAKlvF.....EGVPHG..L....PNEK......RAR
  663-  864 (179.91/54.07)	THV..EPS.HPNKEN.KSPvKIL....TGVA.HGLAN.KKRARATeDDEPDV.DQEGADRGG...KRRKAELA..PQPRILGTPKLARStPI.P.SPQKVSAG...TP.S.P...........VCGEIVMRGEDC.VSLGwcFWHRA.CYGC...LLCG..SKHIASG..VKLEEL.FGDMDD..................DL.......ednmgkTRGREIEEPPlcahclveaeLDGMdeRAVVQKGL..................rrmdcvdggLGRT....R..WEASQGQ..................................
  865- 1084 (215.56/66.12)	...P.LPLrIGSHQT..G......APVPESPaYRSPSlRATGQRS.SITNHDRNQQRDAIDAIDPPD.STIYVSINDP..LGEP.AFK..PS.PTKPIPRWMQmllGN.RRQY..........YPDASRQSTPVSpSRVS..STSTQ.QLGPLPERART..SSSISTV..CPQKILnPASTPP......S..........LS..............PRVSSLTRTS..........SGGS..ITDFYRRT.........vedhmkrhtpsswvshepLKRPS..SR..MAYIQGH..Q.....RTVTEV.......STSSAY..ATPPE
 1094- 1342 (180.01/54.11)	ATLPcRPQ.PGLAGTmPSR.HVAFDELPA.Q.LTRTR.HPL.........SAPAVPSSHKHDILTTLIDRMLSRCRRPHLPLRPIIVAS.RL.TA....RSSI...AP..LSTivfhqsrallVTLATIEAQNHL.QRLG..T.........KDHQLPVanKSTAATM..APVENN.PQELLEqqlkdtI..........QDLyqimlqitmytttP..THSSHTA..........LTSS..LQTLSASLqavhttavagapptpdgvppnaqdqlgMPPGVPLHDpaRHVTPGA..L.....PNIPPE..LvqyvENGRNP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.40|      14|      15|     212|     226|       2
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  212-  226 (20.38/16.16)	TPvKKSLKRTSSKAN
  230-  243 (27.03/16.86)	TP.KSTLHRSPSKNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.58|      15|      17|    1351|    1367|       3
---------------------------------------------------------------------------
 1351- 1367 (23.64/22.28)	EL..VRRGNqlMRGKMGAF
 1369- 1385 (22.93/13.78)	QLrdVLAGE..MRSAMPEF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04140 with Med10 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASQGQPLPLRIGSHQTGAPVPESPAYRSPSLRATGQRSSITNHDRNQQRDAIDAIDPPDSTIYVSINDPLGEPAFKPSPTKPIPRWMQMLLGNRRQYYPDASRQSTPVSPSRVSSTSTQQLGPLPERARTSSSISTVCPQKILNPASTPPSLSPRVSSLTRTSSGGSITDFYRRTVE
2) AVHTTAVAGAPPTPDGVPPNAQDQLGMPPGVPLHDPARHVTPGALP
3) HMKRHTPSSWVSHEPLKRPSSRMAYIQGHQRTVTEVSTSSAYATP
4) LQRLGTKDHQLPVANKSTAATMAPVENNPQELLEQQ
5) MDSIEGHASAFRAQPGRFTPVKKSLKRTSSKANLEDTPKSTLHRSPSKNNLQSTPSQAVSGLKCTSSKANLDEHIEKQPLGTTPSKLRVFAPQPQPSPSPVKRVRQQIEDDASSRRPISRDGSSLPRPTSSSNASASLARSGSTLTSSTSPAKATAARTGLPKISQPALTKSPSKASLSGLTQSTSKTDLGELTKSPSKPALGGTAKPAATHDLATLSRTVELKRRIV
6) MSPPRRRSARLASASTPKPKKVSQLSSLTERDETPEEVESTSLDGVVASPHPQPATPASSALKPPMSEMHPSKVHPTATGSSETWLGFRDIKSANVARGKSAMNPQATPSRLSGVPSSSFTFNLTGPAGETGLSTDAQRMMADLREEAAKIKADLVAKRELEKLDEQVNGRKIARAKGKSGRFSAAHMEEFK
7) RFERVKSILRGGKSPAQPAKSAIPQPFTGVSQTPGPRILDKPLPAVP
8) TTPRRKLFKRVDFTPDSKDTPSKSRGEVNYPNLDAILSRMNEPESHGAPREIKSPLPASPNKREGQAPEVPTVPGAFTFRSDRTARFGTGSPAGFGSSPGQLSVRQVRASITPVEEMPGSFPETADLPRATHTSKTPVKSMTAGIKHGLTNEKRARTNTEPFVLNKEGSTPAKLVFEGVPHGLPNEKRARTHVEPSHPNKENKSPVKILTGVAHGLANKKRARATEDDEPDVDQEGADRGGKRRKAELAPQPRILGTPKLARSTPIPSPQKVSAGTPSP
860
1281
1038
1203
194
1
425
473
1036
1326
1082
1238
421
192
471
751










Molecular Recognition Features






MoRF SequenceStartStop




1) ETWLGFRDIK
2) MSPPRRRSARLASASTPKPKKVSQLSSL
3) PSKLRVFAP
4) RFERVKSILRGGK
5) VPFTTPRRKLFKRVDFTPD
83
1
277
425
470
92
28
285
437
488