<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04073
Description |
Mediator of RNA polymerase II transcription subunit 13 |
Sequence | MAKLAVAIFNSTAVSKNFVIYFVYTSDNPQTIVDACAAFKRLFDIYKRALAERKKPAQNELVLQLVSLDYIATSTSLVVLQPFEHIRLCLETYDRCTLFGGPMPSPAVVLEQPITRGIDFQIRNPPSANILQENSAMHIAYAQSVDERWITAAWSDNRGSKQMTASYCLGRRGKPLSRGFTDVVHEIWTTTFDLISIWKVHWRIIVTKVGPMDQQEISDWITLAQTETKASVTLTLLAVDTNPSLQLIPAISKVPITAQSAFYSTPVSTPQSSIVSPEQVGNPATPKGGPTSSQTATTPGADANTSEADTDASLVDVTDTVWAAIASHRLNVSHSLVDPNPALISGYLIKRGWSNTEDPPAVLEVNVVHSEGNPRMHELLLREMLTYFRGLCTIARARSVTNEEGDVRPWHVAAAEKGVEALYQLM |
Length | 426 |
Position | Kinase |
Organism | Diaporthe ampelina |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Sordariomycetidae> Diaporthales> Diaporthaceae> Diaporthe.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.076 |
Instability index | 43.74 |
Isoelectric point | 5.88 |
Molecular weight | 46838.79 |
Publications | |
Function
Annotated function |
Component of the SRB8-11 complex. The SRB8-11 complex is a
regulatory module of the Mediator complex which is itself involved in
regulation of basal and activated RNA polymerase II-dependent
transcription. The SRB8-11 complex may be involved in the
transcriptional repression of a subset of genes regulated by Mediator.
It may inhibit the association of the Mediator complex with RNA
polymerase II to form the holoenzyme complex.
ECO:0000256 RuleBase:RU364134
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP04073
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 112.15| 34| 232| 104| 138| 2
---------------------------------------------------------------------------
104- 138 (57.16/43.72) PSPAVVLEQPITRGIDfQIRNPPS...ANILQE..NSAMH
339- 377 (54.99/36.63) PNPALISGYLIKRGWS.NTEDPPAvleVNVVHSegNPRMH
---------------------------------------------------------------------------
|