<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04054

Description Uncharacterized protein
SequenceMPLMLDNAVPVDLNDVDDLFGDGVGLSLPDRSHDRPLSLKVDDVRSRGCCQTIAWSKSGTVASITPDGQFLQLRFLRCNPADGTWDLSKPTTCELIKGSSGIPLVHLEWGSTNLPELAIVDAVGRVVIVGFSISLNHPFITRKYDTDSIDDANAVVGAHWLAVAPQNQQKSYNILYGPAIRNGNIYQYESSFVHAGGPSHPHSSKSALFCVTISGMLKMFWSQNNNRMEETTMELESVNSLDELVTHAALASDKRFLLVAVATSSKQLRLLKIEIQWGGPGSQPDKNPLPQNARLSPSLVEKHLAATTWLQTGPGDDASMAELSHLHVLPSIIDNTGKSTVSPMIVAIRTRTPTSGSYQTAQTIIDRWEAVSEQRHNLHPAFEQLGNRRNSEVSEQTGYTRLRKLEPITINKVLISFQPAQFGKLLVLTMSDGTVEYRDRFTFEEVYATEDTNRVMSLRQVGWNFSEEGSCQQVAFSPTHCSMVQMSDEGKIKWCKLQYPLGDIGNSYQEVRYGATIAGLTVAAASALWHQANYDDLLAIVAPYTSKRRFIHDWITEIIKVHKIQVDYSEELHHDLLMRNTPLQSCLSFMNSLGFKGETHPRTFQGKFAMIDLNVRNVVVLITLAMNTPVTVREKMTPLDEHEVVEALAGCAKWSLDLLSWLTDSLFTLMNDSEFIARLEPKRFGEVTPYLQKRNDVSLHLLLSSSSRSFLICVCRRIVHLESLSERAIEFYRGQSANMDQTGVPKAANPKLQQAYQKMQHITTTSLVKVADFEKLLNVLGGDVRQAYQAFLPNMVKSSSQNPQGKQIDLAVKAAQVSLELNMLLAAGPPAPFLPVIKKFFTKELPAFRALCDPSKLFFANYDLLGVQDDESSLARNGSRFVYVDLFKRVEMKLGAQQWRRCTRCACVMEDVFGSRPGYSFVLGQQRKCACGGLWALLPKGKLML
Length945
PositionTail
OrganismTrichoderma harzianum (Hypocrea lixii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Hypocreaceae> Trichoderma.
Aromaticity0.08
Grand average of hydropathy-0.177
Instability index41.33
Isoelectric point7.09
Molecular weight105340.46
Publications
PubMed=26067977

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04054
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     425.10|     135|     194|     584|     735|       1
---------------------------------------------------------------------------
  584-  735 (198.15/143.20)	QSCLSFMNSLGFKGETHPrtfQGKfaMIDLNVRNVVVLITLAM....NTPVTVREKMTPLDEHEVVEALAGCAKWSLDLLSWltdSLFTLMNDSEFIARlEPKRFGEVTpyLQKRNDVSLHlllSSSSRSFLICVCrriVHLESLSER.AIEFYRGQ
  786-  925 (226.96/121.88)	QAYQAFLPNMVKSSSQNP...QGK..QIDLAVKAAQVSLELNMllaaGPPAPFLPVIKKFFTKELPAFRALCDPSKLFFANY...DLLGVQDDESSLAR.NGSRFVYVD..LFKRVEMKLG...AQQWRRCTRCAC...VMEDVFGSRpGYSFVLGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.96|      38|     194|      72|     112|       2
---------------------------------------------------------------------------
   72-  112 (65.74/53.25)	QLRFLRcnpADGTW..DLSKPTTCELIKGSSGIP.LV..HL...EWGST
  267-  312 (52.22/32.73)	QLRLLK...IEIQWggPGSQPDKNPLPQNARLSPsLVekHLaatTWLQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.74|      60|     207|     119|     185|       3
---------------------------------------------------------------------------
  119-  185 (83.45/70.93)	IVDAVGRVVIVGFSISLNhpfiTRKYDTDSIDDANAVVGaHWLAVAPQ..NQQKSYNILyGPAiRNGNI
  332-  393 (98.29/58.45)	IIDNTGKSTVSPMIVAIR....TRTPTSGSYQTAQTIID.RWEAVSEQrhNLHPAFEQL.GNR.RNSEV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04054 with Med16 domain of Kingdom Fungi
Unable to open file!