<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04033

Description Uncharacterized protein
SequenceMAQKIDFNALKARTMGSGDDEEAVTVDTRGLISKVLARYSGKWTVLREMIQNAADANATKVTVRFETLPSMTVPLPSAADSTTMIKHTISHHTLRRLLISNNGLPFSEKDWARLKRIADGNPDETKIGAFGVGFYSVFDDCEEPFVSSGKDAMAFYWKGNALFTRRLQLNEKANPETTFVLDYRNDTSPIPSLMQLCQFLSSSLTFVSLECIELWLDDWNVLRLCKKTAPSLSLTLPRDIETKTQDGLMKVTAVTREVAQVDAHWMQVVEWNPNGSLLRNGIRDTTVSLRGFLSRLTLQGVSDKPVSSEKKDHPGNNGDLTKMSMASVFLHINTASIQASISQSLSNELERATRKPPPKKTSLSVLTPSYDTSMASAASGSQPEFLSSILPSKGGRVFIGFPTHQTTGLNAHISAPSVIPTVERESIDLNTRYISRWNMEMLRAAGIVCRVAWSAEMASIKSSILSAKDPARRPKIRKDDIMSVIPEAIHAANQFVFRESTPSSLLGQTMEDAFWTCNKNAAIEVLSTCGIVQNHEARIASKDLNFIDSIPVLPDEFVEGAKEFVKKLTVLGLVNEVTVSDIKRELEASTLRSHQITEFLAWLGRRALTGQLDPHSVKSLLTVAVANTEDENGNTTGLIVFSGITSFLNPQRIPADLPLPPTVIPFKYTKTLAKQELEAFDWIELPLVPWVRWLVSNAANRDVLPVDHDITQTPSFSTQVLPVLSKQWESLSPNYKQLLVDQLQPHTVIPTRVGMKRPAETYFPSVRLFDDLPVVHGVQGVKEKFLAALGVRKTVELGVIFERLLNAPEPSDGNSSGRRKWSHVDLIRYLASVSNDIPTNDIKRLKDTSFCMAELSTSPNGSKTPSQKRYKVLDLFEPNDALRVLGLPLLEWPGKYLPNSNEGQFLTRLGLRGFPTAAEVIQVMAKAASSNNWTLHGKALSYFLAEYDANGYGTFDYNKVTEPFLPIEKPDPGLFGENTTSPHAAMLGVPAEGLYDVSLPGKCFTDPGAALFGFRILRGDLHRHASKLGVKQHPRLSDCLDVVIQNPPSTKRDARVIFRYLAGRASELTTRDMGRVSRAEIVPVSTTDEVAKGQPPHRVAPKFCYLGEGEDYKDIFDFVDFGHEANLFLMAVGSKREPTKIELAQMVVKEPARISSTFQSADKYLKLLRTLAEDLSTLKKNKELLQEMKRSAFLLASKDITSAAKEKTEKPTKERIIKSGEEEEEEEDDDETGEESIREWTLTAAKDVVVVDDIQSFILFKEHVLAAPQEEVLENFYIALGAVPLSRLVEERAHWGAIAADQRPASKLLKLINERTRLFLHDHPRDTIQHDSRWVENHLQVQVVQSVAITRSLKDRRISYKQERRAIVTELSKTWVMRICPGRYDFYEISQALSHLILSRPKLHSTLTLEMLLKTDLLELRARGYNVERILRQKAQEAKIAEDRRQKQLEEERKRLQEKEDTWMKEQAHGQVPEQHAQPAMPGVFPDSPSNKSIGSSSPQDGSERAQEKRRGLFSNFTRHFKDGNRSSWNPFSEISPPSTSSSPPPAPPPGEPKTPLPEAPVTVGSPLELQKKLMSAVQSSRPHGASGVFSRPQTNQIADMKSYCDEKPGHDLEFVANLPCRLNVLFSKTVPDRSAFLAKNFAGMNIFGSILIDCADVFSLRSDSLSVFYEPGSKTIAFNRSGSIFCNYHFFQQLHEAELIKTPSGSRGDAMTYWWVILCHELAHNLVGDHSSAHSFYSEGFVTQYFPKMAAKIAAVCAQPGTQASTQGQGSMRPTLRIAHSTFEMAPLLGDWSASAAGSDSQAASQGITQKSILYIDAYDSFSYNVVAMLEEVLKAQVTVMMIDAEWPDGNMVEFLQHYDAVVLGPGPGDPHVPTDVGVMADIWNLSSANILPVLGICLGFQSLCLHHGISIGRLPEPLHGQVHRITTAQRDIFEQVQDLEVTLYHSFYAQFKDGTHSTLPGETSTVVITHGLDFLAWLSIQPDDTSLTETQIPMAVRHMEKPFWGVQFHPESCKSDRTACDELLRKWWEMSLNYNKRHGRGGYGRLPADIIRPLSEVNSLSDAAFSMLNWSTSSSKHSAFRTLTLENLDAERICESLNSPGSPLVLFQSNGRHSVMSVPSPGSWRLEYYIQTQTLRMETLQGLNENQSLEKVVSVCQLWDVLRYLMDMKKVESGDSEVPFWAGFLGYFSYELGLACLAHPKAEDSLQEHCCTKSSSFTEDPADVSLLWTDRSIVVDNQTGRITVQSTREEDNQPSAWLDATLQYLKDLAEVDLPTAAKNVAADAEFLDPILRRGITHFPDEETYLKRVEACKDELRAGESYELCLTGETSITLPSPETTEGRSMFPWKMYKRLWKYNPAAFSAYAKLGNVKIISSSPECFLNWDRESTLEMKPMKGTVRKSDEMTLEKARQILGSTKEMAENLMIADLIRHDLYGICGTGGVHVEKLLEVEDHGRVYQMITHVKGVVDQRRPGYAARSMPRLQSPNMSVYGLTALQRCLPPGSMTGAPKERSCVHLSSIEGRKRGVYSGVMGFLDLGGGGSFSVLIRTAFTSSDDNSPVQKWRIGAGGAVTILSTAEGEWDEMLTKLRTVCGIFTPLDAKPSNGKIALLSNISPRSAHLLSYGDNSEMAGTQEPSSLEEILWRSPPHVQMMGGYLHSNNILFYFAESPFFDATSNNASLAIQANYNEAFRHFVETREAFEGRLKTMQGLEFVVAYDPLQAAAQSNTQFARDPSNIWVIRKQTRRKRAGLDDEVVVLATFFVVGDCIYMAPSVASVVGNRILSAVTSLTSLLKTASTLPIFTPSHGHTYLPPAPKSTDPSQPGVQSQGSKENTPMPDVDASSKAAAALVSSQAQQTSGSTFQDLKTLAESFNLLSRYGDEFMDENPLVGEPGSFILSKAGDTDRGATAKQPPPPSTIPGRVATPQVKVDTPGKTSEKAAPSGAEESKLRRKKSKLGS
Length2958
PositionHead
OrganismAspergillus rambellii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.08
Grand average of hydropathy-0.321
Instability index46.11
Isoelectric point6.22
Molecular weight328078.94
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
4-amino-4-deoxychorismate synthase activity	GO:0046820	IEA:UniProtKB-EC
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
folic acid biosynthetic process	GO:0046656	IEA:UniProtKB-KW
glutamine metabolic process	GO:0006541	IEA:UniProtKB-UniRule
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tetrahydrofolate biosynthetic process	GO:0046654	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04033
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     595.33|     195|     572|     940|    1160|       1
---------------------------------------------------------------------------
  948- 1160 (288.86/243.41)	DANGYGTFDYNKVTEPFL...PIEKPDPGlfGENTTSPHAAM.LGVPAEgLYDVSLPGKCFTDP.GAA.LFGfrilRGDLHRHAS.KLGVKQHPRlSDcLDVViQNPPSTkrdARVIF.RYLAGRASELTTRDMGR.......VSRAEIVPVsTTDEVAKGQPPHRVAPKFCYlgEGEDYKDiFDFVDFGHEANLFLMAVGSKREPTKI.......ELAQMVVKEPARISStFQS
 1523- 1739 (306.47/197.33)	DGNRSSWNPFSEISPPSTsssPPPAPPPG..EPKTPLPEAPVtVGSPLE.LQKKLMSAVQSSRPhGASgVFS....RPQTNQIADmKSYCDEKPG.HD.LEFV.ANLPCR...LNVLFsKTVPDRSAFLAKNFAGMnifgsilIDCADVFSL.RSDSLSVFYEPGSKTIAFNR..SGSIFCN.YHFFQQLHEAELIKTPSGSRGDAMTYwwvilchELAHNLVGDHSSAHS.FYS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.28|      29|     569|    2320|    2348|       2
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 2320- 2348 (55.07/32.55)	GE..SYELCLTGET..SITL...PSPETTEGRSMFP
 2890- 2925 (39.21/20.72)	GEpgSFILSKAGDTdrGATAkqpPPPSTIPGRVATP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.65|      48|     311|    2030|    2090|       3
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 2030- 2090 (67.50/71.50)	WEMslnYNKRHgrgGYGRLPADIIRPLSEVNSLSDAAFSMLNWSTSSskhsafrTLTLENL
 2349- 2396 (89.15/56.82)	WKM...YKRLW...KYNPAAFSAYAKLGNVKIISSSPECFLNWDRES.......TLEMKPM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.78|      48|      84|     618|     665|       4
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  618-  665 (82.00/46.90)	KSLLTVAVANTEDENGNTTGLIVFSGITSFLNP..QRIPADLPLPPTVIP
  701-  750 (79.78/45.42)	RDVLPVDHDITQTPSFSTQVLPVLSKQWESLSPnyKQLLVDQLQPHTVIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.26|      47|     954|     891|     943|       5
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  891-  943 (75.74/53.90)	EWpgkylPNSNEGQFLTR.....LG.LRGFPTAAEVIQVMA...KAASSNNWTLHGKALSyF
 1847- 1902 (74.53/38.65)	EW.....PDGNMVEFLQHydavvLGpGPGDPHVPTDVGVMAdiwNLSSANILPVLGICLG.F
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.46|      20|     567|    1912|    1932|       6
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 1912- 1932 (32.78/21.03)	SIGRLPEPlHGQVHRITTAQR
 2480- 2499 (36.68/19.54)	SMPRLQSP.NMSVYGLTALQR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.33|      24|    1378|     587|     616|       7
---------------------------------------------------------------------------
  587-  616 (35.64/38.33)	EASTLR.SHQItEFLAWLGrraltGQLDPHS
 1964- 1988 (40.69/25.35)	ETSTVViTHGL.DFLAWLS.....IQPDDTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.38|      17|     158|      67|      83|       9
---------------------------------------------------------------------------
   67-   83 (29.76/18.51)	TLPSMTVPLPSAADSTT
  228-  244 (28.62/17.44)	TAPSLSLTLPRDIETKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     365.88|     127|     163|     255|     399|      18
---------------------------------------------------------------------------
  255-  399 (187.97/162.78)	TREVAQVDAHWMQVVEWNPNgsLLR.NGIRdTTVSLRGFLSRLTLQGVSDK.PVSSEK..KDhpgnngDLtkMSMASVFLH.INTASIQASISQSLSNEleratrkPPPKKTSLSVLTPSYDTSMASAASGSQP.EFLSSI..LPS...KGGRVFI
  421-  565 (177.91/113.59)	TVERESIDLNTRYISRWNME..MLRaAGIV.CRVAWSAEMASIKSSILSAKdPARRPKirKD......DI..MSVIPEAIHaANQFVFRESTPSSLLGQtmedafwTCNKNAAIEVLSTCGIVQNHEARIASKDlNFIDSIpvLPDefvEGAKEFV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04033 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKEKTEKPTKERIIKSGEEEEEEEDDDETGEESI
2) GDEFMDENPLVGEPGSFILSKAGDTDRGATAKQPPPPSTIPGRVATPQVKVDTPGKTSEKAAPSGAEESKLRRKKSKLGS
3) PSHGHTYLPPAPKSTDPSQPGVQSQGSKENTPMPDVDASSKAAAALVSSQAQQTSGSTFQ
4) QEAKIAEDRRQKQLEEERKRLQEKEDTWMKEQAHGQVPEQHAQPAMPGVFPDSPSNKSIGSSSPQDGSERAQEKRRGLFSNFTRHFKDGNRSSWNPFSEISPPSTSSSPPPAPPPGEPKTPLPEAPVTVGS
1204
2879
2804
1436
1237
2958
2863
1566










Molecular Recognition Features






MoRF SequenceStartStop




1) ATPQVKVDTPGKTSEKAAPSGAEESKLRRKKSKLGS
2923
2958