<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP03988

Description RNA-dependent RNA polymerase
SequenceMDETGILNEGEIFCPVLSERFYREILVRKNVVVTRSPAFHPGDVQLVNAIDVPEDSPLRKLHNCVVFSQKGNRDLPSKLSGGDLDGDLFNIIYDDRLKPQKIAEPADYPRAVDFSKTGKPVDVSRIPKYPPYRPDFMAPGPRVHIAESIELLSSEREHIYGEEDDNDDDDDGGRRLIRYYKSKRVLGQLYRAIDEKEFLQDLQTLPKERPVNLLTALWQYVEHETAGFIWTHCIATAREIKEIYEDDLQDLMYQYSDTSWKTSLTEIEVFIGNIMGESHKQTKRQKEASKSMREDYDRLVDWTISMILGQDSDSEDQALERSIACFWVALDDATARYKSSKKKRLRSFAWIAAVYSAVCKTAMQTRQTSPMPWHQAYAAKLVLFYFAESPFFDPTSNNASLAIQASYNESFRHFVETREAFEGRLKTMQGLEFMVTYDPLQAAAQSETTFAHEPSNIWVIRKQLRQKRPGMEDDVVVLSTYYVVGDCIYMAPSIASVVGNRLLSAVTSLTKLLNTASPLPIFTPAYGHTYMPPGPKQLTDTSQQTTAAAAQSQQSKEGTPVPDGQAPTKAPLAGANVSSSAFQDTRSLMEALTLLSKYGDEYMDENPLVGEPGSFILTK
Length619
PositionHead
OrganismRasamsonia emersonii CBS 393.64
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Rasamsonia.
Aromaticity0.10
Grand average of hydropathy-0.456
Instability index54.62
Isoelectric point5.24
Molecular weight69875.05
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA binding	GO:0003723	IEA:UniProtKB-KW
RNA-directed 5'-3' RNA polymerase activity	GO:0003968	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
gene silencing by RNA	GO:0031047	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP03988
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     231.51|      48|     182|     364|     411|       1
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  115-  163 (41.91/20.85)	.SKTGKPVdvsriPkY.PP.YRPD....FMAPGP.....RVHIAESIELLSSerehiYGEE.
  364-  411 (81.94/47.64)	QTRQTSPM.....P.WHQA.YAAKLVLFYFAESP..FFDPTSNNASLAIQAS.....YNESF
  517-  552 (35.49/16.55)	.....SPL.....PiFTPA.YGHT....YMPPGPkqLTDTSQQTTAAAAQS...........
  554-  602 (72.17/41.11)	QSKEGTPV.....P.DGQApTKAPLAGANVSSSA..FQDTRSLMEALTLLSK.....YGDEY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP03988 with Med6 domain of Kingdom Fungi
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