Description | Mediator of RNA polymerase II transcription subunit 16 (Fragment) |
Sequence | DSSSPLFSKHVEDIVSNSTSLQVHAFHQAAKLNGRWGYSPFRRRPIGPFHPVGKIALLCVTRAGVIRLLYQNPDHRWAEISAELKTTGHSDRLLTHAALVATQGTLFRALLVRTLLANLRNLGGILIATHSACQKIGLYRVHITWNPAQWDPNQPKQASATHPFPTPSFRIFHSKTENPSSVFTPNRNQSDNSKEHSPAPSSLYSLTRLDIVPGQSDSTGGSASGPWILAVYSNTMHATSHDPQQQAPPSSVIVRWQMETASLSLHPKFDEVISKKNNVQAKVDQSIPPILRNHRG |
Length | 296 |
Position | Tail |
Organism | Rasamsonia emersonii CBS 393.64 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Rasamsonia. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.410 |
Instability index | 50.25 |
Isoelectric point | 10.05 |
Molecular weight | 32691.57 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP03974 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 130.09| 30| 30| 139| 168| 1 --------------------------------------------------------------------------- 139- 168 (61.03/31.68) YRV.H.ITWNPAQ.WDPNQPKQASATHPFPTPS 169- 201 (38.90/17.79) FRIfHsKTENPSSvFTPNRNQSDNSKEHSPAPS 207- 227 (30.16/12.30) TRL.D.IV..PGQ.SDST...GGSASGPW.... --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) ILRNHR 2) WILAVY | 290 227 | 295 232 |
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Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab