<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP03945

Description Catalytic domain of Cyclin-Dependent protein Kinase 8-like Serine/Threonine Kinase
SequenceMLKEHLDSRKPSGTGYTSKVRVRDKYHIVGFISSGTYGRVYKALGKNGQKGEFAIKKWAGSVRYFVSLGSLTSRRFKPDKEGEIIQYTGLSQSAIREMALCSELDHANVVQLEEIILEDKAIFMVFEYTEHDLLQIIHHHTQPHRHAIPAPMVRSILFQLLNGLLYLHTNWVLHRDLKPANILVTSSGAIRIGDLGLARLFYKPLNSLFSGDKVVVTIWYRAPELLMGSRHYTPAVDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIIEIMGLPTKDIWPGIVSMPEYSQLQSLAMSRAPGHFPRSSNLEGWYQSCLKNGGYASSSGAGTPGADGYDLLSRLLEYDPTKRITAQEALEHPYFKNGGPISANCFEGFEGKYPHRRVTQDDNDIRSGSLPGTKRSGLPDDSLMGRASKRLKE
Length431
PositionKinase
OrganismAspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.09
Grand average of hydropathy-0.329
Instability index41.56
Isoelectric point9.28
Molecular weight48375.03
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP03945
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.56|      29|      42|     307|     335|       2
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  316-  358 (42.54/25.32)	RSSNLEGWYQSCLKNGGYASssgagtpgadgydlLSRLLEYDP
  361-  392 (47.02/28.73)	RITAQEALEHPYFKNGGPIS...........ancFEGFEGKYP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP03945 with CDK8 domain of Kingdom Fungi
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