Description | Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MMQSHHPSPARLGLTASSPSLPPNPAAVNPTSSPPQGNPSAAAAVGAAAAAAPTLTTSPSLLPLLPPLPRAQALLQLISALASNLFELSPSRAAWISAYRGSLPTFLPSPSSAPPPPLPAPISSTKEALSLLNTLQTQLFEAVAELQETLDLQDARARLAREARAKDASILAFAKKLREAHHVLDRLVDDYADYRRDPKRPRGAAAADDPEPVSDGDFGASLHSKLNLDDVLTYAHRISYTTFAPPEHGAGLPLRGALPPAPQENEMRMSQLYQFADLDVGVPKSQEAKERTAAEGDATPLFQPSPTQEAAVLPITVPHPHGWRNGALPLEIPLPPPGWKPGDPITLPPDGILAGVKGEEPRASVPQMPVVVPAMVPKAQEPIQVRHVDLDINNSSSSDEYSSDVGSSEEDDED |
Length | 414 |
Position | Middle |
Organism | Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Oryzoideae> Oryzeae> Oryzinae> Oryza. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.333 |
Instability index | 59.42 |
Isoelectric point | 5.00 |
Molecular weight | 43796.76 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141 |
GO - Cellular Component | mediator complex GO:0016592 IEA:EnsemblPlants |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP03679 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 135.24| 32| 67| 33| 68| 5 --------------------------------------------------------------------------- 37- 68 (53.75/17.10) GNPSAAAA...VGAAAAAAPTLTTSPS....LLPLLPPL 94- 118 (43.19/11.77) ......AW...ISAYRGSLPTFLPSPS....SAP.PPPL 281- 318 (38.29/11.32) GVPKSQEAkerTAAEGDATPLFQPSPTqeaaVLPITVP. --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EPIQVRHVDLDI 2) YADYRR | 381 191 | 392 196 |
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