Description | Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MMQSHHPSPARLGLTASSPSLPPNPAAVNPTSSPPHGNPSAAAAVGAAAAAAAAPTLTTSPSLLPLLPPLPRAQALLQLISALASNLFELSPSRAAWISAYRGSLPTFLPSPSSAPPPPLPAPISSTKEALSLLNTLQTQLFEAVAELQETLDLQDARARLAREACSKDASILAFAKKLREAHHVLDRLVDDYADYRRDPKRPRGAAAADDPEPVSDGDFGASLHSKLNLDDVLTYAHRISYTTFAPPEHGAGLPLRGALPPAPQENEMRMSQLYQFADLDVGVPKSQEAKERTAAEGDATPLFQPSPTQEAAVLPITVPHPHGWRNGALPLEIPLPPPGWKPGDPITLPPDGILAGVKGEEPRASVPQMPVVVPAMVPKAQEPIQVRHVDLDINNSSSSDEYSSDVGSSEEDDEDYNLNQTGP |
Length | 424 |
Position | Middle |
Organism | Oryza meridionalis |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Oryzoideae> Oryzeae> Oryzinae> Oryza. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.330 |
Instability index | 58.21 |
Isoelectric point | 4.98 |
Molecular weight | 44798.82 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141 |
GO - Cellular Component | mediator complex GO:0016592 IEA:EnsemblPlants |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP03575 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 5| 209.58| 43| 81| 8| 51| 1 --------------------------------------------------------------------------- 8- 36 (37.41/13.27) .............................SPARLgLTA.SSPSLP...PNP...AAVNPTSSP.PH 37- 84 (47.84/14.90) GN.....P.SAAAAVGAAAAAaaaptlttSPSLL.......PLLP...PLP.raQALLQLISA.LA 85- 120 (32.68/ 7.83) SNlfelsP.SRAA.....................wISA.YRGSLPtflPSP...SSAPP...P.PL 283- 323 (41.04/11.74) GV.....PkSQEAKERTAAEG.................dATPLFQ...PSPtqeAAVLPITVPhPH 324- 352 (50.62/16.20) GW.....R.NGALPLEI........................PLPP...PGW...KPGDPITLP.PD --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) IQVRHVDLDI 2) YADYRR | 385 193 | 394 198 |
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Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab