<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP03510
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MGRFSNGVLGALSFAALLASVPLIGAGAYLLDHPASECQRLVRVPAVALGGAALLLSLMAIAGITCCRGAALLWAYASAMFLLIVGMFFVTAFVFVVTNRGVATAVSGTGYGEYRVRDYSEWLRARIEDYETWHRIESCMADAAVCGGPLAGINPGEFYRQHLPLIQSGCCKPPVYCGYERVNETFWMAPARGLDAADVDCLEWSNDQAVLCFRCNACKASVLDTARRNWRAVAAINVAVLAILMLAYSLACCSMRDRSRPRPLKYPLQLGWKLKVRNPSSSPVVAMLPQSQSSSLQRLNHVEQRIVQLMQLVGAVMEELGNSQGPRPEKVVAHCREYMLAIKEIQTTLREEIKSACEYRPFEKSDYSARIANEISCKKVEYG |
Length | 383 |
Position | Head |
Organism | Oryza meridionalis |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade>
Oryzoideae> Oryzeae> Oryzinae> Oryza.
|
Aromaticity | 0.09 |
Grand average of hydropathy | 0.153 |
Instability index | 42.54 |
Isoelectric point | 8.62 |
Molecular weight | 42109.58 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | integral component of membrane GO:0016021 IEA:UniProtKB-KW
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP03510
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 86.42| 26| 40| 11| 36| 1
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11- 36 (46.43/33.08) ALSFAALLASVPLIGA.....GAYLLDHPAS
48- 78 (39.99/27.43) ALGGAALLLSLMAIAGitccrGAALLWAYAS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.58| 15| 41| 105| 123| 2
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105- 123 (24.48/26.51) AV.....SGTGYGEYrvrdYSEWL
144- 163 (23.09/13.70) AVcggplAGINPGEF....YRQHL
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