<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP03212

Description Uncharacterized protein
SequenceMRGKTPNTLALYQPQPPQWLPETHKAIHLGYPLYDPAHANQPEDVLSEQNVSKGYTTPYAVEQGRDWGSANGDAAAALRESSALDRLQDLVNQVYIRRSQQLPPLPNSSFRVPGRLTLNDSKRQAWFADLANPDVPLTKLGKNVPHGAKGHDLLELMYTNNIAMPRAVWFLRVFGANETAGLRNKPNYNPTQYSIEWAGVVTSYIKKQLSEITLPSAPRPGVNIKQSFKGVLHDKASRERWVNRFAYCLSLLKSFYTGGMVDHRVFLSWLVGIMASCNLAQAAVVARIAEEYLDDMTTSRPLAHHFVDACLARLAEIAASPSKEHLLDAEALLVIILQRLCIVLPDAFVSPKLWHTHQAILASVMAADGLDISETSGAQSARQVLENNFQNIRRRNEAMLFVNMPQLAPAQLGSSVQEIKLLNSISKTTNMSTISFFTDDLEDTKRKLDLLLTWCVTPLQFGDHRAFAAVTLLMKWRQRASNRTIRRPDQFLQDELFKWLDRSEVAADPKVISTVSMVFGKLVDKQLFSYDRYIQRLVARSEPGLAVDNPTESRHRAFLRCIPVSDEAQMLSRRNNLYGVGRREVPEDANEKAMRKELRTILPLFSGTSDMHTSTTALYEQCSTIISSPRFDLNSTMKGWLLPALQKCFATADITLLAVVIRTYCIAVELMAKTKCYSCLLQLTLTFIEHAPNLEALAIAIDTIRRYVTIWTCMDVVGSILHALQTAYIAYKSRGTASRILLSFIMELDNNVHLSEDDRRQIVADEQSLILALHPHSFNQPITLPDTIPEILGLASTTDPDAPVTLASTLWAQHRSFPAWVLRVWGNTVSSLRHLPAMFPDLDLRRACALRYADFLLHIDEHNSTAMDDAVLKWFSSTAGRQEFSELTADVWDGFAILLLSLVVRGILRATTIMQGLVYPVWQLCASVGAAQYTEQMDVCISAANYLAKILLLSQEGLGDIPPVDMFDIQRLQARRADVYSDDMQFKSLVESIPIMVSVENNEVVRAELREDMKTMRLQLCEDDGFREGTFRNLEAVREAFEDAMKSLESTSPDVGDRTMNALQTIFSSGNPDGQGIEISSWPEKSSMLSPWMISATTIQFQLSLKQMERSPTHADATKVERLDTMIKMMFDHSLSPDERGFMAQMTHGAGSTVAGKLINNGLRHVTDVLRDGGEQTIMRVGDSFRILVYIADPLRREKVPMLMLQPDVQDALFKVIVQAFEDIGRQCEAGQDITTLHERLILMTRVLQFDLGFEGVWTPNTVPLCRPLCDMLFKVVMFSAQGENFHSVVFSLLFDTLLFLIDETPPQNKTGGVADIFSPYPSSEAFDLDHDIPPEEVKRLRSLLSTRLSIAKVANLASVRRDNSGHLVDDGPVINRPWEWIEHIGEPVADAKELEREKDEKRRLKTNCLVKNTGSLPLETFGARVTGDAILESRTEDPIIENALRTFEDGVSTDSVFKRDWREARLPSLEEEASSASGAARKGKASTSGMQQQQHEAVFSPGGHRSSPTASTQSWTSGRRGSPNVHSSASEVIDVDALPYPLPNRTGTKRKATASVSDDEVVIIEGPLPSSSKSKKGKSVASKTKARKK
Length1590
PositionKinase
OrganismCylindrobasidium torrendii FP15055 ss-10
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Physalacriaceae> Cylindrobasidium.
Aromaticity0.07
Grand average of hydropathy-0.211
Instability index47.23
Isoelectric point6.15
Molecular weight177551.89
Publications
PubMed=25683379

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP03212
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     267.27|     111|     434|     342|     775|       1
---------------------------------------------------------------------------
  342-  407 (41.41/614.08)	IVLPDafvspklwhTHQAI..LASVMAADG.LDISETSGAQS......ARQVLENNFQNIRRRnEAMlFvnmPQL........................................................................................................................................................................................................................................................
  587-  648 (70.63/69.76)	...........................................................................apaqlgssvqeikllnsiskttnmstisfftddledtkrkldllltwcvtplqfgdhrafaavtllmkwrqrasnrtirrpdqflqdelfkwldrsevaadpkvistvsmvfgklvdkqlfsydryiqrlvarsepglavdnptesrhraflrcipvsdeaqmlsrrnnlygvgrrevpEDANEKAMRKelrTILPLFS...GTSDMHTSTTALYEQCSTIISS..PRFDLNST..MKGWLLPALQKC
  782-  925 (155.24/ 0.00)	ITLPD.........TIPEIlgLASTTDPDApVTLASTLWAQHrsfpawVLRVWGNTVSSLRHL.PAM.F...PDL..................................................................................................................................................................dlrracalryadfllhiDEHNSTAMDD...AVLKWFSstaGRQEFSELTADVWDGFAILLLSlvVRGILRATtiMQGLVYPVWQLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     146.69|      46|     434|     986|    1082|       2
---------------------------------------------------------------------------
  693-  740 (72.28/27.29)	NLEALAIAI.DTIRRYVTiwTCMDVVGSILHALQTAYIAYKSRGTASRI
 1033- 1079 (74.41/37.54)	NLEAVREAFeDAMKSLES..TSPDVGDRTMNALQTIFSSGNPDGQGIEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.45|      33|     430|     519|     577|       3
---------------------------------------------------------------------------
  228-  267 (52.16/20.87)	FkGVLHDKA..SRERWVNRfayclsLLKSFYTGGMVD......HRVFL
  519-  559 (49.29/68.17)	F.GKLVDKQlfSYDRYIQR......LVARSEPGLAVDnptesrHRAFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.16|      47|    1435|     102|     149|       8
---------------------------------------------------------------------------
  102-  149 (79.11/55.36)	LP.PLPNSSfRVPGRLTLNDSKRQAWFADLANPDVPLTKLGKNVPHGAK
 1539- 1586 (73.05/45.90)	LPyPLPNRT.GTKRKATASVSDDEVVIIEGPLPSSSKSKKGKSVASKTK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP03212 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KRDWREARLPSLEEEASSASGAARKGKASTSGMQQQQHEAVFSPGGHRSSPTASTQSWTSGRRGSPNVHSSASEVIDVDALPYPLPNRTGTKRKATASVSDDEVVIIEGPLPSSSKSKKGKSVASKTKARKK
1459
1590










Molecular Recognition Features






MoRF SequenceStartStop




1) ASVSDDEVVIIEGPLPSSSKSKKGKSVASKTKARKK
2) LPYPLP
1555
1539
1590
1544