<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02972

Description CMGC/CDK/CDK8 protein kinase
SequenceMPLRPHIGLGFPAHAYQKRHVEPHDRSTGYQPKVRITDRYRIIGFISSGTYGRVYKAVGRNGKPVGEFAIKKFKPDKEGEQISYTGISQSAIREMSLCSELHHINVIRLCEIMLEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATIKSIMFQLLNGCQYLHINWVLHRDLKPANIMVTSSGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIIEIMGVPTKDKWPLLPTMPEYNQLNTLANSMASSHHGHHSHHHPHHHHGHYGSRNPPPPPPGGSNLEKWYYSTINHTSAPGGTPPLASLGSEGYKLLAGLLEYDPSKRLTAAQALQSPFFSTGDRVSANCFEGCKNEYPCRRVSQDDNDIRTSSLPGTKRSGLPDDSLIRPAKRQKE
Length452
PositionKinase
OrganismFusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium> Fusarium oxysporum species complex.
Aromaticity0.08
Grand average of hydropathy-0.499
Instability index45.69
Isoelectric point9.19
Molecular weight51042.91
Publications
PubMed=20237561

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02972
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     342.22|     111|     175|      18|     144|       1
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   18-  144 (166.74/141.47)	KRHVEP.HDRSTGyqPKVRITDRYRIIGFIsSGTYgRVYKAVgrNGKPVGE.FA.IKKFKPDKEGEQISYTgiSQSAI....REMslcselHHInvIRLCEIMLEDKCIFM..VFEYAEHDLL....QIIHHHTQQPRHP
  196-  319 (175.48/105.32)	RRFDKPlHSLFSG..DKVVVTIWYRAPELI.LGSY.HYTPAI..DMWAVGCiFAeLLSLRPIFKGEEAKMD..SKKTVpfqrNQM......QKI..IEIMGVPTKDKWPLLptMPEYNQLNTLansmASSHHGHHSHHHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.01|      25|      48|     330|     354|       2
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  330-  354 (49.19/32.17)	NPPPPPPGGSNLEKWYYSTINHTSA
  379-  403 (41.82/26.22)	DPSKRLTAAQALQSPFFSTGDRVSA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02972 with CDK8 domain of Kingdom Fungi
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