<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02963
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MARGDDQPLSIRPSPVADRKPQNIAEFIARANAQPGGFRAINEAKLREELAQEEAEYGAALDRDADMADGDQDEDDDQDAPRDLQEVRMEMLKNLDAAGNTALLTLDFLSLLISKQNPTQAGVTLSQGLRDMVGIGTLGTDRLDNPPVTPAKVQEQENIALGLALIQTNKARDAAEAASAFLEKEVTVEGKYWEEIAAVQKSGWSISRVPQERHTLGVRFGFSEAAPEYRNSLAPMRRGNGGAVQLDCGRLGGVSERVVVTYERDGQVTGRSALPAETAADAPLEERVLEARNTIFSQELWHELTREARTLAAYDVKPYDSRLICDIDPASKSRVILELVPLGPQASSDDDLPDNQIAETISLALHTLLSYAHRQNELTRTRPIPPHIPRSRGQQTHALLRPIIARLMHLHNVQVVTKHIGVLVQSLQRAGFPSRFVLHTAPISLTDSDPANQGPNQLASSQIMIRNMLQPIEFNIKLTILPNVSFTVRGRTFLMPVTATYYYVITPPNSPLSAACAPYREGYPDANALADYLGTATTRLLVEHYLAILPPPWSKGIQGNAILNAKNEDCRMVFTVTEEPALHLKSTSIVDGQLVSQEWTWSDDATKIYVQDIIDTEVSKLNL |
Length | 623 |
Position | Head |
Organism | Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium>
Fusarium oxysporum species complex.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.322 |
Instability index | 44.92 |
Isoelectric point | 5.12 |
Molecular weight | 68570.64 |
Publications | PubMed=20237561
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
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Interaction
Repeat regions
Repeats |
>MDP02963
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 62.72| 19| 330| 8| 31| 1
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8- 27 (31.66/25.13) PLSIRPSPvADRKPQN.IAEF
341- 360 (31.06/13.18) PLGPQASS.DDDLPDNqIAET
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 117.85| 36| 224| 196| 234| 6
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196- 234 (54.33/43.85) IAAVQKSGWSiSRVPQerHTLGVRFGFSEAAPEYRNSLA
424- 459 (63.53/40.04) VQSLQRAGFP.SRFVL..HTAPISLTDSDPANQGPNQLA
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