<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02912

Description Uncharacterized protein
SequenceMQRYHGAGCTSAVNNSAIGGASARDTSRADSSSLPPNFQFNSRRQSQLASYKLKCDKEPLNCRLGPPDFHPQSQTCPEETLTRENVQQGYKDTINGLEDSKEISLTQIQAFTKPVVLKCRDAIRKCLRAINESRAQKRKAGQVYGIPLSGSLLSKPGVFPEQRPCSEDFRKKWIEGLSQQNKSLCSLADQVPLGYKNRTLIEVLIRNNVPLLRATWFIKVTYLNQVRPGSAISTGSLDKAQLSRTELWTKDVIDYLQHLLDEIFSRNNSHFTQHGRDRLPQMHNAASLQHRSAPASATLDGEEPSLQFKWLYVVRLLQWHHAEGLVLPSLIIDWVLNQLQEKELLEILQLLLPIVYGVLETVILCQTYVRNLVAIAIRFIREPSPGGADLVDNSRRAYTVSALVEMLRYLIQAVPDTFVALDCFPLPTCVVSHAFSDGGFLSKSSDDAGKIKSNSADAYVVKVKGFDSQYQSLSFDHVVSTIHKCADNLVKGASAGYPSQSMAKAVQTLDKALLHGDLIEAYKHIFDDLCDGAVGEGWVAEVSPCLRSSLKWLQTVNLSLICSVFFLCEWATCDFRDFRTAPPHNLKFTGRKDFSQIYLAIHLLKLKRKEWQNPEYKKGRASGLYSTAKNTSYQNNYSRRNLLGNIYEAKSNGKYVNGRSSSSSDIFDSPGPLHDIIVCWIDQHEGLKGEGGKRLQLLILELIGSGIFYPQAYVRQLIVSGIIDISRPMADLDRRKRHHRILKQLPGQYMLDILEEARIAKGSELLEAVNVYSNERRLALHNLLFDQHNCANTSHVSTNDKKSHSTSGRDGAFQVSGDQWKTLQSSKTFRRDVDLEGLKASISVLLQFPSLSSTSADSGVEESQGSSKRSVGSTCNKPDMFEGAPGYEDCKRVKRQKLSEDKSLYLQAPSPIPSDDEDTWWMRKGQKNIESFKSDPPHKSTKQVSRGRQKTVRKTQSLAQLAAARIEGSQGASTSHICDNKINCSHHRTEVETLKPVDGIRTTHFGDIVSIEKGLKQLRFVEKRIVMVWLISVVKQLVEESEKSVAKAGQYGRPFIAADEKSPLRWKLGEDELSVILHLMDVSCDSVSAIKFLLWLLPIVSSNPGPTVHSGRNSLRVPRNVDNCACAVGEAYLLSSLRRYENILIAADLVPEALSAIMLRAAAIMATNGRVTGSGTLVFALYLLKKYGKVASVIEWEKKYKGACDKRLFSELESGQQEGDFGFPFGVPGGIEDPDDYFRKKITGGRFSRVGLSMRDMVQRHVDDVLHSILGKERKLVAAGAPKTPAVEKGGDGYQVAQQIIMGLMDCIRQTGGAAQEGDPGLVSSAVSAIVGNVGSTLAKIPDFTGGSNYSNYQPSISSLSFAKRILRIHLICLCLLKEALGERQSRAFEVALGTEASSALAVAFAPAKSSRGQFKLSPDAPESSANISGDNLNSSAKSTLGRTTKMSAAISALLLGAIVHGVISLERMVTVLRLKEGLDVVQFVRSTKTSSNGNARSVGAFKLDNSFEIYVHWFRLFVGNCRSVCDGLVLELLGEQPIVALSRMQRLLPINLVFPPAYAIFAFVIWKPFILSSNIASREDIHQLYQSLTMAIGDAVKHIPFRDVCMRDTRGFYDIIAADTTDSEFAALLELNGLDTHLKSMAFIPLRARLFLNAIIDCKMPYSAFTHDEGNRVSGHGESKALRGENDSKQGKLIRALDALQPAKFHWQWVELRLLLNEQALIDKMENHDMSLVDALRSSSPSSERASPSENEKVFIEIILTRLLVRPDAAPLFSEVVHLFGRSLEDSLLMQAKWFLGGMDVLLGRKTVRQRLINIAETKNLSTKTQFWKPWGWSYSGGDPVTNRGEKKNEATFLEEGEVIEEAVESKKCAKGSQIDVEGSNISQQHVTEKAFIKLILPCIDQSSANSRNTFANDLIKQFSTIEQQVKLVTRGISKQTGTASSIEVSTNKSNSRKSIRGASPGLARRTMAPAESVPPPPAALRASMSLRLQFIVRLLPIICADGEPSSRNMRHMLASVIFRLLGSRVVHEDVDLSFNFKQLKRDAELVSSIASSEIYRDSLFDRLLLVLHGLLSSCQPSWLRSKTANDYSGFDHEALESFQVWSLSFPC
Length2109
PositionKinase
OrganismGossypium raimondii (New World cotton)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.237
Instability index47.38
Isoelectric point8.94
Molecular weight233818.60
Publications
PubMed=23257886

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02912
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.35|      16|      16|     177|     192|       1
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  177-  192 (27.50/18.24)	LSQQNKSLCS..LADQVP
  193-  210 (22.85/13.77)	LGYKNRTLIEvlIRNNVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.96|      21|     101|    1893|    1913|       2
---------------------------------------------------------------------------
 1893- 1913 (39.25/24.27)	FIKLILP..CID..QSSANSRNTFA
 1992- 2016 (31.71/18.11)	FIVRLLPiiCADgePSSRNMRHMLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     201.31|      67|     101|    1217|    1288|       3
---------------------------------------------------------------------------
 1217- 1288 (111.34/80.09)	QEGDFGF.PFGVPGGIEDPDDYFRK..KITGG.RFSRVGLSMRDM.VQRHVDDVlHSI...LGKErklvAAGAPKTPAVE
 1316- 1390 (89.97/53.39)	QEGDPGLvSSAVSAIVGNVGSTLAKipDFTGGsNYSNYQPSISSLsFAKRILRI.HLIclcLLKE....ALGERQSRAFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.00|      28|     298|     572|     599|       4
---------------------------------------------------------------------------
  572-  599 (54.25/32.97)	TCDFRD.FRTAPP.HNLKFTGRKDFSQ...IYL
  874-  906 (38.76/21.38)	TCNKPDmFEGAPGyEDCKRVKRQKLSEdksLYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.31|      55|    1147|     787|     847|       6
---------------------------------------------------------------------------
  787-  847 (81.52/66.01)	QHNCANTSHVSTNdkKSHSTSGRDGAfqVSGDQWKTLQSSKTFRRDVdlEGLKASISVLLQ
 1937- 1991 (93.79/56.75)	QTGTASSIEVSTN..KSNSRKSIRGA..SPGLARRTMAPAESVPPPP..AALRASMSLRLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     244.00|      80|    1147|     386|     473|       8
---------------------------------------------------------------------------
  386-  473 (119.19/97.40)	GGADLVDNSR..RAYTVSaLVEMLRYLIQAvpdtFVALDCFPLPTCVVS....HAFSDGgfLSKSSDDAGKiKSNSADAYVVKVKGF.........DSQYQSL
 1535- 1629 (124.80/77.49)	GEQPIVALSRmqRLLPIN.LVFPPAYAIFA....FVIWKPFILSSNIASrediHQLYQS..LTMAIGDAVK.HIPFRDVCMRDTRGFydiiaadttDSEFAAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.36|      16|      17|     246|     261|       9
---------------------------------------------------------------------------
  246-  261 (28.20/20.92)	ELWTKDVIDYLQHLLD
  262-  277 (29.16/21.93)	EIFSRNNSHFTQHGRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.39|      17|     103|     850|     867|      15
---------------------------------------------------------------------------
  850-  867 (24.11/23.06)	SLSSTSAdSGVEESQGSS
  957-  973 (28.28/20.66)	SLAQLAA.ARIEGSQGAS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02912 with Med12 domain of Kingdom Viridiplantae
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