<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02766

Description Uncharacterized protein
SequenceMREKKDGQQASDLPVYESHPPGWLPKIHGSADLGYAGFHPPRPGQDEDALSEPNVKNGYILAQAVSVETFSVQALINESLNMPESLTKLEQLMNEVFLHRADRMPAIPPSTFKIPTRVTLNDAKRQAWFADLANPEVPLHRFGRSVPHGAKGHDLLDLLHTNNVAIPRAVWFLRVFGANETAGLRNKPTFVPTQYSIDWANVVTGYMKKQLSDIALPSAPRPGLNIKQTFKRVLADADSREKWMSRFTYCLRLLRTFYTEDLVDHRTFLTWLVQQMSTCNLAQAGFLTRLTDEYANDILTNRALARPLAEACLAKLFEICTTPAHEFLKDTEDILKVLIQRICLALPDAFVSPKMWSVYSQLLDGVISANDMNFPAHHCMDQNSRDLRRSLSDNLLDVKRKNEAMLFRGPIAQVSARLGAAVVDVKLLNSISGNTDMSAIPFFPANTNDASFKEKLDMLLTWSVTSLQYGDHRPFAAVTLIRLWRDRAHDRASRRGVATPSEFLQDQLFDWLDVSEVAGEAANIRDVALLYGKLVKHEVFSYASYIQRLIARGEIGLSYTEGSQSRHQLFLSWIPLFNATSSLTNQRKVILHGPRARETPEDAIEREIRKEIRVVLPDLFEGTSASPWISTKSLFEQCQTLINATRFEQVRTFRQWLLPVFKKRLSRAEGNFPSLFTPYLVAVELMSLTKCFHSMLDLTLAMLEQCTDAESTSSLLGTFDRYLTIWNCMDVMRTIVKSLDDLHQVLKHRGAQSRPLLTLLMKFDNGRYLGEASRSRICSDITAFTLALRPILDRPEIVPEVLPEILLLVGDPEDNAPSILANSLWIKYRASPDWAWRVWDNTVASLRQIPSIAPGSEARRTHALRYGAFLWRVDQHLPNGLDCDVLQWFLGPGKNEVMALNADAWDILKTVLLFLVVHGSLSITTILQGLVYPAWKLGTTEGTGQSSLSETYLSAANKLTSLLLLQDDDSNNTIPPFDLAEVQAIRTRRQAAYDEPHFALLVGSIPMLISLENNGELNEILRAEFTTLRCRICQDSGFRQGAYRNLDVVRETFENSPYLIDQDPTSENLSQKAITGLRMILGDSTDEANIYDWPEVTCILSPWKIAATTIQMQLQVKKLGRTLSHESTAVSAAANLNKLTSMLFHHTRTAEEAYYVGEMARGADSAVAARFLNNGFQYMANYLSGLQSSIDSSSNECIQRVGELLRVLIHVSQPFRNSPADFLTAESGVLEAFICAIDGGFRKMEIHLQNGTLASASTDNFILLSRLLQFALSFKHSWTPKAKDTCVSLSSLLFHFALQSATEDNLSMTAYPIFIDTLFVLYDELPNDSKSITFDPYRYYPNVSVDAIPLDMPPEYHQQILSLLVPSTSPSVVTNLQNTTHDAEGNLVFGSAVVNKPWEWIENLGEPTVTDPKEDERSREERAREHPHLKYLVKNSSSISLENFGTRHTSEGRKQSMQDDAAGQLEGCLRFFEDSVSENIYIRDWRETRWGAEPSPALPGRIRGDFDPEAAHAPELSKTQMQRASPTLSIISHSSTQGTSSSLRQQHHQSPNSRHSGSTYEVIDVDSLPGTSSSVRGKESMKRKVGTISDDDEVEIIEGPVNIRSTHVAKKPKAAKAPTSTRGKARKK
Length1628
PositionKinase
OrganismHypholoma sublateritium FD-334 SS-4
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Strophariaceae> Hypholoma.
Aromaticity0.08
Grand average of hydropathy-0.266
Instability index45.36
Isoelectric point6.16
Molecular weight182600.41
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02766
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.88|      10|      19|      12|      21|       1
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   12-   21 (21.26/10.88)	DLPVYESHPP
   32-   41 (21.62/11.19)	DLGYAGFHPP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.44|      18|      19|     253|     270|       2
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  253-  270 (30.22/18.69)	LLRTFYTEDLVDHRTFLT
  272-  288 (26.59/15.54)	LVQQMSTCNLA.QAGFLT
  289-  304 (17.63/ 7.73)	RLTDEYANDILTNRAL..
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.55|      14|      19|     799|     816|       3
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  793-  806 (23.95/16.26)	DRPEIVPEVLPEIL
  811-  824 (23.60/ 6.72)	DPEDNAPSILANSL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.29|      19|      19|     506|     524|       4
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  506-  524 (33.01/19.33)	D..QLFDWLDVSEVAGEAANI
  526-  546 (28.28/15.60)	DvaLLYGKLVKHEVFSYASYI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.86|      23|      30|    1522|    1544|       5
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 1522- 1544 (40.58/26.32)	QRASP.......TLSIISHSSTQGTSSSLR
 1547- 1576 (36.28/22.72)	HHQSPnsrhsgsTYEVIDVDSLPGTSSSVR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.40|      19|     384|     217|     250|       6
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   42-   68 (27.61/ 7.28)	RPGQdedalsepNVKNGY..ILAQAVSVE
  221-  241 (29.79/35.92)	RPGL........NIKQTFkrVLADADSRE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.32|      43|     384|      69|     112|       7
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   69-  112 (70.20/50.72)	TFSVQALiNESLNMPESLTKLEQLMNEVFLHRADRMPAIPPSTF
  461-  503 (77.11/51.39)	TWSVTSL.QYGDHRPFAAVTLIRLWRDRAHDRASRRGVATPSEF
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.44|      19|     592|     139|     159|       8
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  139-  159 (30.10/27.06)	LHRFGRSvpHGAKGHDLLDLL
  742-  760 (33.34/21.88)	LHQVLKH..RGAQSRPLLTLL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.80|      30|      38|    1420|    1453|       9
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 1420- 1453 (42.49/35.43)	EERAREHPHLKYLvknSSSISlENFGTRHTSEGR
 1460- 1489 (53.31/31.58)	DAAGQLEGCLRFF...EDSVS.ENIYIRDWRETR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.81|      24|      25|    1248|    1272|      13
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 1248- 1272 (34.99/20.00)	LQNGTLASAStDNFILLSRLL.QFAL
 1274- 1298 (39.82/19.20)	FKHSWTPKAK.DTCVSLSSLLfHFAL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.20|      18|      18|    1108|    1125|      14
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 1108- 1125 (29.66/19.36)	TTIQMQLQVKKLGRTLSH
 1128- 1145 (28.54/18.35)	TAVSAAANLNKLTSMLFH
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.35|      25|      30|     370|     397|      16
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  380-  409 (36.07/33.35)	MDQNSRDLRRSLSD.NLLDvkrknEAML....FRG
  411-  445 (25.28/ 6.30)	IAQVSARLGAAVVDvKLLNsisgnTDMSaipfFPA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02766 with Med12 domain of Kingdom Fungi
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