Description | Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MEADRGPSQSKNQPSSFTPASRIAELNEIDRSISTLLSAASDALGILSNSPASVSQEKALKNSESARAAFTAAAEAYFSTLSSIEVRLRRQVYALEEAELIRPGDDKDARKGRALGGDSGITTAGGGPLDPSWLNARVSDKVGDGMKRELLARAREFVERVGRDTPDGNVEAGKSGAVQGHDNDEEMG |
Length | 188 |
Position | Head |
Organism | Rhinocladiella mackenziei CBS 650.93 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Rhinocladiella. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.591 |
Instability index | 42.39 |
Isoelectric point | 4.99 |
Molecular weight | 19876.62 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP02725 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 143.83| 45| 48| 82| 127| 1 --------------------------------------------------------------------------- 82- 127 (68.84/45.10) SSIEVRLRRQVYALEEAELIRPGDDKDARKGRAlGGDSGITTAGGG 132- 176 (75.00/45.27) SWLNARVSDKVGDGMKRELLARAREFVERVGRD.TPDGNVEAGKSG --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) FTPAS 2) GMKRELLARAREFVERVGRD | 17 145 | 21 164 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab