<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02700

Description Uncharacterized protein
SequenceMRASPAFKASTPRRGAKARHPETTNAQSLGKPDSDQDHGTSHWSSAGEASGVQASTGSRTLAKAGAKVKRFDNDPSLRVHRHRKTKYSYRIGIRLPREKLLAFPQYDGRVKDFVHRWSASFVTLKLPPSKLRAIDAAQRRLPLAVVGPVPPLPPSLPAVSTARTSSLPAFPPSLLLTAGPSSFSDADTQPDSPFTAYPSPEAEADKSCIQAKAALQQNLPLASNTGPFSAYDPRELFPAPSAATPSSSSLLSAPFQIGTTFEDLPVSERLIRNSTMAPVKDTSSVHNSIKGIIQHLTDIQLQTHGYIPQTQDLLVDKLTDLTNSLAELKRLTSPQESPNNYIHQVAIAPEIVDYVDDGRNPDIFTRDFVEIVQRGNAVIHGKQRAFRDFTEVYARKLKEGIPGVSAQVDRVLRNAGFDEQDESKSSTNGAHDAERAVDAHEHGHEPDHGSRNE
Length453
PositionMiddle
OrganismPhialophora americana
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Phialophora.
Aromaticity0.06
Grand average of hydropathy-0.581
Instability index44.36
Isoelectric point8.75
Molecular weight49354.49
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02700
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.01|      23|      24|     126|     148|       1
---------------------------------------------------------------------------
   95-  125 (25.91/12.51)	LPREKLLAFpqydgrvkDFVHRWSASFV.TLK
  126-  148 (40.56/23.80)	LPPSKLRAI........DAAQRRLPLAV.VGP
  170-  190 (33.74/18.54)	FPPSLL..L........TAGPSSFSDAD.TQP
  207-  227 (21.81/ 9.35)	...SCIQAK........AALQQNLPLASnTGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.46|      33|      34|     287|     320|       2
---------------------------------------------------------------------------
  287-  320 (52.88/40.36)	NSIkGIIQHLTDIQLQTHGYIPQT..QDLLVDKLTD
  323-  357 (52.58/35.32)	NSL.AELKRLTSPQESPNNYIHQVaiAPEIVDYVDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.58|      10|      24|     364|     374|       3
---------------------------------------------------------------------------
  364-  374 (14.84/14.92)	FtRDFVEIVQR
  386-  395 (19.74/13.71)	F.RDFTEVYAR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02700 with Med10 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MRASPAFKASTPRRGAKARHPETTNAQSLGKPDSDQDHGTSHWSSAGEASGVQASTGSRTLAKAGAKVKRFDNDPSLRV
2) VDRVLRNAGFDEQDESKSSTNGAHDAERAVDAHEHGHEPDHGSRNE
1
408
79
453










Molecular Recognition Features






MoRF SequenceStartStop




1) AKVKRFD
2) MRASPAFKASTPRRGAKARH
3) RAVDAHEHGH
4) SLRVHRHRKTKYSYRIGIRLP
66
1
435
76
72
20
444
96