<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02693

Description "Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"
SequenceMADLKDDLTEKAHFDPNWIAWNGGTLHSNNVLFYFATSPFFDHVSGNQSLFTQWAGTPNQNDILGTRAKFEANLRHQRGIQYVVEHDPLEEQVVLDGPNGPEKSNVWVIRKQNRENERDDSITILGYYYIVNNVIYQAPSVASVLNYRLLNTVSALSKVFTAPADLSFFSVAHGHTYHKPIQQSAPQNILSASQQGNEPPPTPGSAPAPQPATTEKAAAPPEAQEETNGGSRTAWDALRLTLQFGKEYVDELPLVGEPGNFRFSKSRDANMTAGQTRGQGLATPTGTPSQSRAASAMPVTSSNQPAGTKGTRAPEKIVTLSEGAAKDLKQQKFTIDAEPSDTIAQVKEKIAAEKGWESSQQKLIYAGKVLADANTVESYKIEEKGFIVCMISKPKAAPAAKSGSPSTPAPSTSTSTSTPAAPVAPQPNPSTVSNLPSTPTPAQSTTTSAAAGSGFNDPSAFLIGNRNEATIREMEAMGFPRPEIDRALRAAFFNPDRAIEYLLSGIPDNIQSEQRQAATGATASNPASPPAPQPAQPAQPAQPAQAASPTGDEPINLFEAAAQAGRPGGGRRAPAGGQGGVATNMDFLRNSPHFQQLRQFVQQQPAMLEPILQQLAEGNPELAQMIGSNQDQFLQLLAEDAQDTLPPGATQIHVTEEERDAIERLCRLGFPRDQVIQAYFACDKNEELAANFLFEQPDDEEQ
Length702
PositionHead
OrganismFonsecaea pedrosoi CBS 271.37
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Fonsecaea.
Aromaticity0.07
Grand average of hydropathy-0.550
Instability index51.98
Isoelectric point5.02
Molecular weight75467.76
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
damaged DNA binding	GO:0003684	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
nucleotide-excision repair	GO:0006289	IEA:InterPro
proteasome-mediated ubiquitin-dependent protein catabolic process	GO:0043161	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP02693
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     213.37|      27|      29|     394|     420|       1
---------------------------------------------------------------------------
  197-  220 (30.09/11.04)	....NEPPPTPGSAPAPQPATTEKAAAP.
  299-  324 (26.87/ 8.96)	VTssNQPAGTKG...TRAPEKIVTLSEGA
  394-  420 (46.41/21.62)	PK..AAPAAKSGSPSTPAPSTSTSTSTPA
  425-  451 (42.33/18.97)	PQ..PNPSTVSNLPSTPTPAQSTTTSAAA
  496-  517 (25.62/ 8.15)	DR..AIEYLLSG.....IPDNIQSEQRQA
  518-  544 (42.06/18.80)	AT..GATASNPASPPAPQPAQPAQPAQPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.87|      12|      22|     128|     139|       2
---------------------------------------------------------------------------
  128-  139 (23.15/19.68)	YYIVNNV.....IYQAP
  147-  163 (15.72/10.62)	YRLLNTVsalskVFTAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.50|      32|     123|     223|     261|       4
---------------------------------------------------------------------------
  223-  258 (52.66/48.53)	AQeetnGGSRTAWDALRLTLQFG..KEYVDELPLVGEP
  577-  610 (55.84/32.08)	GQ....GGVATNMDFLRNSPHFQqlRQFVQQQPAMLEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.09|      20|     188|     458|     490|       6
---------------------------------------------------------------------------
  471-  490 (36.28/42.70)	IREMEAMGFPRPEIDRALRA
  662-  681 (36.82/15.43)	IERLCRLGFPRDQVIQAYFA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP02693 with Med6 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) APAAKSGSPSTPAPSTSTSTSTPAAPVAPQPNPSTVSNLPSTPTPAQSTTTSAAAGSGFNDPSAFLIGNRNEATIREMEAMGFPRPEIDRALRAA
2) LLSGIPDNIQSEQRQAATGATASNPASPPAPQPAQPAQPAQPAQAASPTGDEPINLFEAAAQAGRPGGGRRAPAGGQGGVATNMDFLR
3) PIQQSAPQNILSASQQGNEPPPTPGSAPAPQPATTEKAAAPPEAQEETNGGSRTAWD
4) VGEPGNFRFSKSRDANMTAGQTRGQGLATPTGTPSQSRAASAMPVTSSNQPAGTKGTRAPEKIVTLSEG
397
502
180
255
491
589
236
323

Molecular Recognition Features

MoRF SequenceStartStop
1) INLFEA
555
560