<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02662
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MEQLEPLKQNQLEQTDDFASEAFFDQNTLEQQIQQLDPTNGLNAAANVGPPPDPTIIEQLQRRWFCGYQERVAWSRLGHIATISDDSSKVRVGCLRFSCESKSWELYERVTLPTLFEDAVGLLFSGHGLELAIVDAKGRLCIYHCSHLALNRFMLGKPNNLDEIHDSAQIIGMAWLNQDRQERPRNVVTHATKNDTRWLHTNSRAKPLGPFFSRGLVVVHRSGTVAFWYQRNDGQYLRSAGHLSTTNDMLYSHASLTLTADQKMMIAVHSLEGEISVCYMSIDWNPLKLSENNLPALSFEFVSTKVFAQPPGSPTMPDLYDPDSWHLSHLELMHSPEAEKEPSAQPAVVAILTGINKTVNIGDPGYLAGSMIKKWTLTSVEQKLHPLFESLPTKGSGMTGHVPILTIQAQLEKAEQAIVTVHHVDGIQAFVITTSENRTDFLSSDDFSPLSYAASITETASMAQSGFTYPYTNIYSPAFSINACLRADVGNDDKTQLAAMEFQVQGPTQQPLDPHLDAAIAALNLAFARACWSNASIDDVLMCALHTLPHDTLPSVVMAMYRTLFRDTEFINEKTQGSELERIFHKQVMGRVMAYHALLVAYSPQLTSITTTDGRVGCWSLSAQWAWVASNIRHTATLLFMNLRDVQHASLTVSQDYTDMLCLNIRWGLAVIRWIISAILEVSDRETNPEMFDSKTGRLGDVKGDGSQGLVALVLNIHCSRVFLVAFIRAVRAYAKNAEPKTRHQLQVLQTIQQHTTGKGITFQAIEAILEFRWAAAGDVDGDIAATTVRQLEMMATGVVPESYQGTIKLLLTKLFNSQAGLRAKMLLDRLKLFTDRVDLDYVFLNHDVLGKLPDDVKGRRVIYDVHRKRPILKGVLEPGGTDEPIVRRCLRCGSFSADIVVPPPDWLSKTVGALLTKCVCDGNWVIEPWKKYSGES |
Length | 937 |
Position | Tail |
Organism | Exophiala xenobiotica |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Exophiala.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.150 |
Instability index | 41.83 |
Isoelectric point | 5.97 |
Molecular weight | 104422.99 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP02662
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 49.73| 13| 15| 540| 552| 1
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540- 552 (25.59/17.74) VLMCALHTLPHDT
556- 568 (24.14/16.31) VVMAMYRTLFRDT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.25| 14| 16| 809| 822| 2
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809- 822 (23.54/15.25) KLLLT..KLFNSQAGL
825- 840 (19.72/11.63) KMLLDrlKLFTDRVDL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.61| 15| 15| 118| 132| 4
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118- 132 (26.45/17.20) DAVGLLFSGHGLELA
135- 149 (30.16/20.66) DAKGRLCIYHCSHLA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.39| 10| 21| 175| 184| 5
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175- 184 (19.89/12.32) WLNQDRQERP
198- 207 (19.50/11.93) WLHTNSRAKP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 41.27| 12| 15| 847| 859| 9
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847- 859 (18.03/15.57) HDVLGKLPdDVKG
864- 875 (23.23/14.45) YDVHRKRP.ILKG
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