<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02635
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAEAEQAQQIPEAAYPAPPPFWRHFTLANEEELRKIEESSTENQTPPKLPLHLAYLRPPPPPPAIAEFYTTFGQKQIIDPTKPSSLPTDQLLFNPDEPNLNHAVLLSKLTKSLLLNFLELTSILSLDPTKHEEKMADIRQLVLNIHVVINIYRPHQARESVKEMLMGILEDGQKEIDECDRLKERVEEFLQDMGTAGSPSEDVQIQGPARMDDEVSHDRMMEKQRKLWNRIHDMT |
Length | 235 |
Position | Middle |
Organism | Phialophora americana |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Phialophora.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.622 |
Instability index | 62.53 |
Isoelectric point | 5.01 |
Molecular weight | 26987.45 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02635
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 83.53| 23| 41| 3| 25| 1
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3- 25 (46.70/21.78) EAEQAQQIP.EAAY...PAPPPFWRHF
42- 68 (36.83/15.94) ENQTPPKLPlHLAYlrpPPPPPAIAEF
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 57.60| 17| 47| 78| 94| 2
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78- 94 (31.70/20.55) IDPTKPSSLPTD..QLLFN
126- 144 (25.90/15.52) LDPTKHEEKMADirQLVLN
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