<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02530
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSSAVATGSLAEHRAQASLDVLPAELQNTIMEEKFAQIKQQRQDARTVLHEAKQRTRNQQTDQQILLLMQADERLAALLSQAADSMRALLPPVAHTDPSVTTPASPAADSTPAHGAKAFEDKAQQWFSILNEVQYSLRSVVRYLRQAQLSPITPPVGPDARLSGRAGSAGRGHNLSLLEAFTDIAGLPGGTTFKLQPLHTTTPSAPSASSSLSTILPESNLSLQALRERQSNWKTLSGSLHQIHQSMIDSTADGSFKTSPELSLLENIKNGCSCDRILIDALVNTNNVA |
Length | 289 |
Position | Head |
Organism | Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Ustilago.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.321 |
Instability index | 50.43 |
Isoelectric point | 6.45 |
Molecular weight | 31102.62 |
Publications | PubMed=17080091
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Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02530
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 336.60| 83| 85| 96| 179| 1
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15- 91 (86.85/40.26) ........AQASLDVLPAElQNTIMEEK....FA.QIKQQRQDARTVLHEAKQRT...RNQQTDQqilllMQADERLAALLSQAADSMR.ALLP
96- 179 (133.50/68.68) TDPSvTTPASPAADSTPAH.GAKAFEDKAQQWFS.ILNEVQYSLRSVVRYLRQAQ...LSPITPP.....VGPDARLSGRAGSAGRGHNLSLLE
182- 266 (116.26/56.26) TDIA.GLPGGTTFKLQPLH.TTTPSAPSASSSLStILPESNLSLQA.LRE.RQSNwktLSGSLHQ.....IHQSMIDSTADGSFKTSPELSLLE
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