<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02503

Description "Unplaced genomic scaffold K443scaffold_245, whole genome shotgun sequence"
SequenceMVSNDGVNDILQRDPMYYYRGRRDGGHRAVSSKYTILGFISSGTYGRVYKAQSLEEDQKIHAIKKFKPDKEGDVITYTGISQSAIREIALNKEIDHENVVALKEVILEDKSIYMVFEYAEHDFLQVIHHHSQTLRQSISTPVLKSLVYQLFNGLLYLHSCHILHRDLKPANILITSSGVVKIGDLGLARLIYQPLQPLFAGDKVVVTIWYRAPELLLGAKHYNKAIDCWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQRDQLLKIFEVVGTPDEQDWPGLVDMPEYQSMKRLDHFSNRLSDWCQSRIRSHLGYDLLRQLFAYDPDNRLTAREALQHKWFQEDPKPTWNAFQTVPGHQIPPHRRITQDEAPSMMPIPAQNTSHQGGHGHMGGPFGQSHSKPGSSASFASLSGGGHYGSHASGGAGNGTHGPSRKKARLG
Length441
PositionKinase
OrganismLaccaria amethystina LaAM-08-1
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Tricholomataceae> Laccaria.
Aromaticity0.09
Grand average of hydropathy-0.455
Instability index47.21
Isoelectric point8.78
Molecular weight49496.65
Publications









Function






Annotated function


ECO:0000256	RuleBase:RU364151

GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP02503
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.44|      18|      30|     385|     412|       1
---------------------------------------------------------------------------
  385-  402 (39.24/30.82)	HQGGH..GHMG.GPFGQSHSK
  417-  437 (28.20/ 6.42)	HYGSHasGGAGnGTHGPSRKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.02|      11|      45|     143|     153|       2
---------------------------------------------------------------------------
  143-  153 (20.96/12.84)	LKSLVYQ....LFNG
  187-  201 (15.06/ 7.54)	LARLIYQplqpLFAG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02503 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KPTWNAFQTVPGHQIPPHRRITQDEAPSMMPIPAQNTSHQGGHGHMGGPFGQSHSKPGSSASFASLSGGGHYGSHASGGAGNGTHGPSRKKARLG
347
441










Molecular Recognition Features






MoRF SequenceStartStop




1) RDPMYYYRGRRD
2) THGPSRKKARLG
13
430
24
441