<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02487

Description ATPase AAA
SequenceMDEHQSTRSAWPDPPNYYKRYSNENLELLKQSKKSGVFPEQSIIKPPVPEFQLEALEPPLPPTDEYTVFDQKWQINDRLPTLQELGVKQIYPQDDAIDRVQELKKLNRSLIVQYLDLLGVLETNPSEYGKHIENISTILLNMHHILNAYRPHQARETLRLLMEHQLAKKRQQTAELRAFSTLMIFVPVENCKPGVAKVSFRELSKLGAQPGAWVQVLDGLGKIYYCSVWPADIPDNHVMASQFIQYESSEQESSSIIPIKSAATAIRVALSYKLNKNAAEEQQLLEFGFIFDEATEAQKNSYIRHTVEGNVICQGATIKKTPLISIQVISTYPEGKPVFLASASQVSVVNGDTTEEDRISELEKSLEAMSIASDLSQSSNTSSLQKAYNALYEVVCFPFLYKDWIHRLGIECPKGVLLYGPPGVGKTFLVSSIARKCKAKMFVIQGPEVFGPFIGESEEKLRIKFIQARDYAIKENVPVILFIDEIDALTPKRDNAQSHENRMVAQLLTLMDGIESRGRLVIVGATNRPNSIDPALRRPGRFDREIHMEPPNATDRYALFEGQMAKMPLESNVDIEALAAMTNGYVAADINSVCREAAMSAVQRASKEKDVEVNVSMMDFTSAFATVGPSMQRGFQVQVDKMKWDDVGGLEDVKKRLKQAVEWPLLYKDSFSRLGLKPPRGILLYGPPGCSKTTLVKVIASSANVAFLSINGAQLYSPFVGDSEKVVRTTFQKARASAPAIIFLDETEAIVGKRNMGNGGDSGDSVQERVLSTLLNEMDGVESAESVLVVGATNRPDMLDAALMRPGRFDQAVYVPPPDEAARVEILKIHTKQMPLDDDVDLLDIAARVGTNYYTGADLQNVCREAAMEALRSMSTAANVTMANFNKSIATIPPSLNEESYMDGRQKSLVESPVALFNVSCSNQNICDPKFFTMKIPENAVLIKQGAEARVFHLPTFLTVPNGCIAKERFKKTYRHPDLDHFLTTRRVAQEARCLYKCKKAGMETPTVYHIDIPTATIFMENITGITVKQRLLDHQTTDYKHVDTNSLAEQIGTSLAKMHSLNVVHGDLTTSNLMLREKDDSVVVIDFGLSSISALIEDKAVDLYVLERAFASTHPQTEFLFEKIVEHYLKHSKQSKQIWTKLEDGN
Length1147
PositionMiddle
OrganismMucor ambiguus
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Mucorineae> Mucoraceae> Mucor.
Aromaticity0.07
Grand average of hydropathy-0.267
Instability index41.69
Isoelectric point5.86
Molecular weight128064.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro
protein serine kinase activity	GO:0106310	IEA:UniProtKB-EC
protein threonine kinase activity	GO:0106311	IEA:UniProtKB-EC
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tRNA processing	GO:0008033	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02487
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     816.37|     233|     264|     391|     632|       1
---------------------------------------------------------------------------
  391-  632 (415.33/361.89)	LYEVVCFPFLYKDWIHRLGIECPKGVLLYGPPGVGKTFLVSSIARKCKAKMFVIQGPEVFGPFIGESEEKLRIKFIQARDYAikenvPVILFIDEIDALTPKR......DNAQSHENRMVAQLLTLMDGIESRGRLVIVGATNRPNSIDPALRRPGRFDREIHMEPPNATDRYALFEGQMAKMPLESNVDIEALAAM..TNGYVAADINSVCREAAMSAVQRASkekdVEVNVSMMDFTSAFATVGPSMQ
  657-  897 (401.04/327.44)	LKQAVEWPLLYKDSFSRLGLKPPRGILLYGPPGCSKTTLVKVIASSANVAFLSINGAQLYSPFVGDSEKVVRTTFQKARASA.....PAIIFLDETEAIVGKRnmgnggDSGDSVQERVLSTLLNEMDGVESAESVLVVGATNRPDMLDAALMRPGRFDQAVYVPPPDEAARVEILKIHTKQMPLDDDVDLLDIAARvgTNYYTGADLQNVCREAAMEALRSMS....TAANVTMANFNKSIATIPPSLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.53|      19|     101|     101|     119|       2
---------------------------------------------------------------------------
  101-  119 (32.79/22.14)	QELKKLNR..SLIVQYLDLLG
  201-  221 (29.74/19.40)	RELSKLGAqpGAWVQVLDGLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.23|      16|      18|     128|     144|       3
---------------------------------------------------------------------------
  128-  144 (25.56/24.58)	YGKHiENISTILLNMHH
  149-  164 (29.67/22.61)	YRPH.QARETLRLLMEH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.67|      24|     913|      15|      38|       4
---------------------------------------------------------------------------
   15-   38 (42.02/38.14)	PNYYKRYSNENLELLKQSKKSGVF
  929-  952 (41.64/37.70)	PKFFTMKIPENAVLIKQGAEARVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.94|      36|     714|     340|     379|       6
---------------------------------------------------------------------------
  340-  379 (51.43/45.73)	LASASQVSVVNGD.TTEEDRISELEKSLeamsIASDLSQSS
 1056- 1092 (56.52/39.48)	LAKMHSLNVVHGDlTTSNLMLREKDDSV....VVIDFGLSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02487 with Med7 domain of Kingdom Fungi
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