<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02466

Description LALA0S02e06678g1_1
SequenceMPSKYLLNPPEDLHSLTADHRNKSIYPDFDPWRHTPIEDKVFLNFVSKGYYNTAKVNFESISSRSSLQESLPAVSGLLADQLSKIVKIREEQVNRVPGKARNLNGTNNLGTKLSGPGFALPKRVTLTDHKRELWLQEISSTNRPLAETVKTIPHGLKRRHLLEQCYQKQVPIARAVWLIKCCFTLEWKISAGKQSSQLHDEMCVKLLQEWSEAMAHILERLVFEMTQYYNEPSKLKKWRKRIAYFLKLLGSCYSLELIDRAAFHHWLVDFVARVENFECLPMTLHILSVFWSGIFPEGQSNSDPQQQFLINKMTETLIYKYYMVSRSKSMINDEQYLINDIKKNDKLATAMSHTLKSFITEIFHKQSLEAFVFTGSNWEIYKKCLYEVLGTDKTMKESPNGSKTSKKLELIVYRNDSLQFNTILNAGEERDPDQTDTHSTDLESIFKPNEILKLRHIDYSLTKLLDENSSGDHWVSCVAQKVNRIDQVIQMILWAINPSRYHHYEAPHLVAKIFLIQINFKNAPLEYGLEDKIWSLIFLFARLKGEDLKSVVSLPRVHQLLNVFIGYGIIKVPTYIRKLISSGVLYLAHSEDKFFHCELLINLKISPVMKSQYNMVLRNVIDANHSFYERFNYDRLTELLESSKISLLSGRFDSMKAVPYSVRLMTSEWYLNLICSPNDGVLTPVTKKDVVEKLNVFCIKLDVCHQFYKWIEFIIYHQLLKDLESLECLTDILIYYEKFFCLLINDHVLLMKTILHLYFDKLVPESPQSQKLILLGDFWTFFLVRFPQVLEIDPDLQAKLIEAKEFEKAKIESAAKISAWMSSKSEDHSDECLKYVTDEFNFPSIFQPNLKAILATETGEDLQLRRTNLRTLMAMNLNEYNKFMSIYLKRKVATNEELAKLISLKVLSLNSVGKVLGNRFLVKLLRTSFWEHGVGFELQKKKFKKHNLLLVLKTYCDDLHEHYEELLEGLAEYCSSRIAEEFLVKVFARIEREGKSSIYSFANDLLNVGVRSSDAVGYHGNSNLKSIEINSTDNGDLTEDEAEVLDLFPRLDFSNIWMFQALTCHYLEDGSCQEQYSQGSSKFILESIEMTNYDIAASKLFDKLRDADILQKTLQVLEVKFLNNGPAEDPKDLSQYYVTVESIVSISRRLNKALKGILPISDEAFTLLKICCQEFATKTSEQLKLLEFRLDIVLKILIVHQKYILKEGLQKKQLLLNDGCLFLKNLCILFYKIDFSLKLKLLLYDLLSSLKAFVVYSSPGKDRQYNDRLSSQVPQELLDLPPFQISSFLPEEKPEDSRGTVQLGIVECDTTKSSTKPYYFIFNRKNGTFDCKFLLRPYHSLGNFQEGESEFNNTPLNLCLFNTVLDRRNPT
Length1371
PositionKinase
OrganismLachancea lanzarotensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.11
Grand average of hydropathy-0.218
Instability index43.70
Isoelectric point7.20
Molecular weight158786.54
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02466
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     204.19|      53|     130|     512|     564|       1
---------------------------------------------------------------------------
  512-  564 (85.97/59.67)	KIFL..IQINF...KNAPL...EYG..LEDKIWSLIFLFARLKGEDLKSVVSLPRVHQLLNVF
  593-  641 (42.49/25.19)	KFFHceLLINL...KISPVmksQYNmvLRNVIDANHSFYERFNYDRLTELLE...........
  644-  697 (75.73/51.55)	KISL..LSGRFdsmKAVPY...SVR..LMTSEWYLNLICSP..NDGVLTPVTKKDVVEKLNVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.58|      19|     265|     938|     956|       2
---------------------------------------------------------------------------
  938-  956 (33.92/22.31)	LQKKKFKKHNLL....LVLKTYC
 1209- 1227 (21.28/10.56)	LQKKQL....LLndgcLFLKNLC
 1237- 1253 (20.38/ 9.72)	L.KLKLLLYDLL....SSLKAF.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     200.89|      48|     359|     723|     770|       3
---------------------------------------------------------------------------
  254-  307 (51.88/33.63)	..SLELidraafhhwLVDFVARVENFECLPMTLH........ILSVFWSGIFP.EgqsnsDPQ..QQ
  723-  770 (87.40/62.44)	LESLEC.........LTDILIYYEKFFCLLINDHVLLMKT..ILHLYFDKLVP.E.....SPQ..SQ
 1085- 1135 (61.61/41.52)	LESIE..........MTNYDIAASKLFDKL.RDADILQKTlqVLEVKFLNNGPaE.....DPKdlSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     381.86|     129|     473|     330|     475|       5
---------------------------------------------------------------------------
  330-  475 (184.68/169.85)	MINDEQYLINDIKKNDKLATAMSHTLKSFITEIFhKQSLEAFVFTGsnweIYKKCLYEVLGTD..KTMKESPNGSKTSKKLELivyrNDSLQFNTI.LN...AGEERDPDQTDTHSTDLESIFKpneILKLRHidysLTKLLdENSSGDHWV
  800-  934 (197.17/131.81)	LIEAKEFEKAKIESAAKISAWMSSKSEDHSDECL.KYVTDEFNFPS....IFQPNLKAILATEtgEDLQLRRTNLRTLMAMNL....NEYNKFMSIyLKrkvATNEELAKLISLKVLSLNSVGK...VLGNRF....LVKLL.RTSFWEHGV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02466 with Med12 domain of Kingdom Fungi
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