Description | Mediator of RNA polymerase II transcription subunit 19 |
Sequence | MELLRGVIKEYDESVKKTSQFTAFAKKSDDSDDDDYDNADEDDEDLLDSVKKDVQDPDSFLALLWAPAEDWINTEVHGKDITAGLSSDVIQNLSRATTMARGPIPKRDWDSSVLGDLPSDKATAPNTPLNLPPMSRPKGGQQPPVGDANRPRRAGKKRSYGDSSFEGSGEAFADDQDVGYSTGEADERGGQKRRKKVLLAT |
Length | 201 |
Position | Head |
Organism | Magnaporthiopsis poae (strain ATCC 64411 / 73-15) (Kentucky bluegrass fungus) (Magnaporthe poae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Magnaporthales> Magnaporthaceae> Magnaporthiopsis. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.944 |
Instability index | 48.96 |
Isoelectric point | 4.60 |
Molecular weight | 21976.76 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364151 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP02440 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 87.96| 27| 29| 85| 113| 1 --------------------------------------------------------------------------- 85- 113 (43.05/32.86) LSSDviQNLSRATTMARGPI..PKRDWDSSV 117- 145 (44.91/28.11) LPSD..KATAPNTPLNLPPMsrPKGGQQPPV --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DEDDEDLLDSVKK 2) ESVKKTSQFTAFAK 3) PIPKRDW 4) RPRRAGKKRSYGDSSFEGSGEAFADDQDVGYSTGEADERGGQKRRKKVLLAT | 40 13 103 150 | 52 26 109 201 |
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