<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02430
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MTNPTQPPLSLRPWPIGDKRPKSLAEFIARVKSAGPEGFRGISEDELRREVELETTGIASTETEMAAPDGDVDMDSGPSAGDEPSTTAVTAETIRTAREEALRNIDIAHQNAMLTLDFVSLLLTKEDPTNAGRTLSPTLRELVGIGTLGADQLAAPQTNASRVQDNKMVATGWKFLDINRSMDSVLSAAARLQKEISLETRYWADVLAVSDKGWSVSRLPHERQTLGVKFGFSESAPAFRNTSLAPMRRSDDGTVSLDAARVANPQRVRVSIERDGVVVGRSMLPQVPAPDAPLESRVMEARNTIFHQELWYEINREGRTLLSFGVRLAEGAVSYELDPHTKAVIHLCDLTDEAPDELGWGPGPDDVLAEAISSALPLLLSYAHRLNLRVRSQPGPPQARQSRAGQPYALLRPVIAYLEHERSLERTTRFVSDLTWVLQSAGYLSASFTLVEPPVSTASPGSSRHTSSSEALLHTFLSPHEFQLQLSITPAVRLSVIGTTQLSAHLCTMYSTRLLPPLEEVPLGPSGPVVPRQNTLRFVYPPSETYPNFREVTHYVRGAVARFLADQAEQLAFSIAGSIEGDGEQRLDFVKSIDGTAVSAVEPDRRSVRFEVNLVGSSGEVAGADEYGSPQLRVYGVWPPLRDGEEMTPQTWTWTVEEAKGGIGKETVEGVCISIFKGLDY |
Length | 681 |
Position | Head |
Organism | Magnaporthiopsis poae (strain ATCC 64411 / 73-15) (Kentucky bluegrass fungus) (Magnaporthe poae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Sordariomycetidae> Magnaporthales> Magnaporthaceae> Magnaporthiopsis.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.287 |
Instability index | 45.39 |
Isoelectric point | 5.15 |
Molecular weight | 74407.87 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02430
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 222.22| 60| 61| 434| 493| 1
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392- 437 (46.04/22.33) ...................SQPGPPQARQSRAGQpyALLRPVIAYleHERSLER.TTRFVSDLTWV
438- 497 (95.49/54.79) LQSAGYLSASF.TLVEPPVSTASPGSSRHTSSSE..ALLHTFLSP..HEFQLQL.SITPAVRLSVI
500- 557 (80.70/45.08) TQLSAHLCTMYsTRLLPPLEEVPLGPSGPVVPRQ..NTLRFVYPP..SETYPNFrEVTHYVR....
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 102.99| 33| 198| 32| 110| 3
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32- 69 (46.75/76.39) KSAGPEGFRGISeDELRREVELETTGiastETEMAAPD
125- 157 (56.24/14.60) KEDPTNAGRTLS.PTLRELVGIGTLG....ADQLAAPQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.51| 16| 89| 265| 298| 7
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265- 284 (22.60/38.34) PQRVRVSIERDgvvvGRSML
307- 322 (29.90/ 7.72) HQELWYEINRE....GRTLL
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