<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02401
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MSQPDGQHDARAANRARFELELEFVQSLANPHYLHSLAQQGILKQPAFINFLAYLQYWKEKDYARFLHYPHALHHLELLQHAQFREEIAKDEWREFLNQKQFDHWRTWRSGRNESSAPPPAQEPPGEPSNQIP |
Length | 133 |
Position | Middle |
Organism | Phlebiopsis gigantea 11061_1 CR5-6 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Polyporales> Phanerochaetaceae> Phlebiopsis.
|
Aromaticity | 0.13 |
Grand average of hydropathy | -0.944 |
Instability index | 57.92 |
Isoelectric point | 6.29 |
Molecular weight | 15781.37 |
Publications | PubMed=25474575
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02401
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 99.78| 28| 33| 32| 62| 1
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32- 60 (47.50/25.68) HYLHSLAQQGILKQPAFINFLAYlQYWKE
68- 95 (52.28/20.56) HYPHALHHLELLQHAQFREEIAK.DEWRE
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