<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02383
Description |
Mediator of RNA polymerase II transcription subunit 8 |
Sequence | MATTSLQQDDLKTLDQMRQRLSQLANNIASLKSDILQGNPLPPWESIQTSASILGNNINSIIEHLSRNADTLNRTVVYPSTNYPGRTQEGLLGQLLRKKLEVQVETWVEEGRAIQESTQESKEDVEELWTWGKEWIGQRVATYILEEAGDNYTVEEREMGIENVNIGLRRKFDEESEEEDEDEDKEMEDVGVEVTTVGKSMGGQVEYGLEEIRRSPDGKSRGVKEILTFATSRNHQPRPVL |
Length | 241 |
Position | Head |
Organism | Oidiodendron maius Zn |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Leotiomycetes incertae sedis> Myxotrichaceae> Oidiodendron.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.795 |
Instability index | 59.56 |
Isoelectric point | 4.58 |
Molecular weight | 27362.97 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364144
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02383
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 89.91| 26| 28| 6| 31| 1
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6- 31 (43.08/28.87) LQQDDLKTLDQMRQRLSQLANNIASL
36- 61 (46.83/31.93) LQGNPLPPWESIQTSASILGNNINSI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 116.04| 36| 63| 109| 147| 2
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109- 138 (47.92/20.82) .................................EEGRA.IQESTQESKEDVE.ELWTWGKEWIGQ
141- 204 (40.82/20.54) ATYILEeagdnytveeremgienvniglrrkfdEESEE.EDEDEDKEMEDVGvEVTTVGKSMGGQ
205- 229 (27.30/ 7.06) VEYGLE................................eIRRSPDGKSRGVK.EILTF.......
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