<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02359

Description Uncharacterized protein
SequenceMQDDWSLQHDPMRLYRFKRDENHRSVASKYNILGFISSGTYGRVYKAQSLDDEGTIHAIKKFKPDKEGDVVTYTGISQSAIREIALNREIDHENIVALKEVILEDKSIYMVFEYAEHDFLQVIHHHSQSLRSPITHAVLKSLVYQLLNGLIYLHSCHILHRDLKPANILITSGGVIKIGDLGLARLIYEPLQPLFAGDKVVVTIWYRAPELLMGAKHYTKAIDCWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQRDQLLKIFEILGTPKEQDWPGLVDMPEYQNMKRLDPFQDRLSDWSHSRLRNDGSGLDLLRGLFIYDPERRLTAKQALLHRWFQEEPRPTWNAFQTIPHHQIPQPRRITQDEAPSMMPMPQNTSHQAAQPVLMPFAQSHSKPGSSASFASLSGGGHYGQASGGNPARKKVRLG
Length429
PositionKinase
OrganismHebeloma cylindrosporum h7
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Cortinariaceae> Hebeloma.
Aromaticity0.09
Grand average of hydropathy-0.423
Instability index51.67
Isoelectric point8.71
Molecular weight48797.30
Publications









Function






Annotated function


GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02359
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.83|      34|      35|     295|     329|       1
---------------------------------------------------------------------------
  295-  329 (55.73/38.14)	QDRLSDWSHSRLRNDGSGLDLLRGLFIYDPeRRLT
  332-  365 (66.09/41.33)	QALLHRWFQEEPRPTWNAFQTIPHHQIPQP.RRIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.33|      78|      96|      44|     130|       2
---------------------------------------------------------------------------
   44-  130 (108.20/97.57)	VYkaQSLDDEGTIHAIKKFKPD.KEGDV.VTYTGISQsaIREIALNREIdHEnivALKEVILEDKSIYMVFeYAEHDFLQVIHHHSQSL
  143-  222 (126.13/82.91)	VY..QLLNGLIYLHSCHILHRDlKPANIlITSGGVIK..IGDLGLARLI.YE...PLQPLFAGDKVVVTIW.YRAPELLMGAKHYTKAI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02359 with CDK8 domain of Kingdom Fungi
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