<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02327

Description Uncharacterized protein
SequenceMAADFWSSSHYKRWMVDRASINQARAVDILYVDNHDPEYFDFLNIYFANAIMKLGRRLSLRQRVIATAIIFFKRFYLKNSYCETDPFLVIAACCYLAAKAEECPVSIKQVALESKAHFSQEIHNVKSTNFDHTRIAEMEFYLVDDLESDLTIYHPYRTLTALCKPDPSSSSSSNTNTATTNNTNPTLPDTEPEEGEAIEYPSPSSGTHSLNPSLNHPIDEGPRYWGTGQGQLELPDGGFQRAWFIINDTYRSNICLIYPPHLIAVAAICLTVVFHPPSRSEIVPHLPSSSSTAKVGQPPDTILTFLASLNVSFPLVATIIQEIVSLWTLWDRYKEDATDTSSAASSASPGGSAGKMSSMSPTKPHQQQLQRLARGSTATLSTLSTSTPTPTAGGGDDPACTTDNNDSSSSHSPLVEEPAILFTPSILSNVLVKMREGRLAIQQATSSNSGSSSSNNNTDGGSNNPGSGSTTPGMGKAANKMLERAQAAG
Length489
PositionKinase
OrganismAmanita muscaria Koide BX008
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Amanitaceae> Amanita.
Aromaticity0.08
Grand average of hydropathy-0.326
Instability index55.00
Isoelectric point5.54
Molecular weight53042.58
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP02327
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.99|      62|     118|     288|     350|       1
---------------------------------------------------------------------------
  288-  350 (99.89/72.96)	SSSSTAKVGQPPDTILT..FLASLNVSFPLVATIIQEIVSLWTlWDRYKEDATDTSS...AASSASPG
  407-  473 (93.11/63.23)	SSSSHSPLVEEPAILFTpsILSNVLVKMREGRLAIQQATSSNS.GSSSSNNNTDGGSnnpGSGSTTPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.43|      23|     171|      72|      94|       3
---------------------------------------------------------------------------
   72-   94 (45.79/29.89)	FKR..FYLKNSY....CETDP..FLVIAACC
  239-  269 (28.64/16.34)	FQRawFIINDTYrsniCLIYPphLIAVAAIC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP02327 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PSSSSSSNTNTATTNNTNPTLPDTEPEEGEAIEYPSPSSGTHSLNPSLNHPIDEGP
2) TDTSSAASSASPGGSAGKMSSMSPTKPHQQQLQRLARGSTATLSTLSTSTPTPTAGGGDDPACTTDNNDSSSSHSPLVEEPAIL
3) VKMREGRLAIQQATSSNSGSSSSNNNTDGGSNNPGSGSTTPGMGKAANKMLERAQAAG
167
338
432
222
421
489

Molecular Recognition Features

MoRF SequenceStartStop
1) GSTTPGMGKAANKMLERAQAAG
468
489