<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02283

Description Serine/threonine-protein kinase SSN3 (Fragment)
SequenceMPLRMRNGPQFHHPSSASSHPFSSSSAHHRYADTHDRPGAFHPRLRVMDRYRIVGFISSGTYGRVYKAVSRVSTVAVRTTTTPSGASSSSATAGQEVAIKKFKPDKEGEQISYTGISQSAIREMSLCSELRHHNVIRLVETLLEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATIKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSGGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGIPTRSKWPLLPMMPEFNQLNTLQSPPSHHSHHHHHHQHHSHSSSSSSTSNLEKWYYNTISNAPQSASSGPSLTSLGAEGYKLLAGLLEYDPTKRLTAAQALQSTFFTTGDRVNTNAFEGLKVEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLLRPPKRVKE
Length472
PositionKinase
OrganismMetarhizium majus (strain ARSEF 297)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Clavicipitaceae> Metarhizium> Metarhizium majus.
Aromaticity0.08
Grand average of hydropathy-0.486
Instability index42.94
Isoelectric point9.47
Molecular weight53053.63
Publications
PubMed=25368161

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP02283
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.29|      23|     175|     150|     172|       1
---------------------------------------------------------------------------
  150-  172 (44.56/23.83)	MVFEYAEHDLLQII.......HHHTQQPRH
  321-  350 (40.73/21.23)	MMPEFNQLNTLQSPpshhshhHHHHQHHSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.07|      31|     119|     245|     279|       2
---------------------------------------------------------------------------
  245-  279 (56.38/46.72)	WY.....RAPElilgSYHYTPAI.DLWAVG.CIFAELLSLRP
  363-  400 (42.69/26.21)	WYyntisNAPQ....SASSGPSLtSLGAEGyKLLAGLLEYDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.01|      42|     327|      81|     126|       3
---------------------------------------------------------------------------
   81-  126 (64.94/46.98)	TTPSGASSSSATAGQEVAIKKFkpdkEGEQISYTG..ISQ..SAIREMSL
  405-  450 (63.06/36.61)	TAAQALQSTFFTTGDRVNTNAF....EGLKVEYPHrrVSQddNDIRTSSL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP02283 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AFEGLKVEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLLRPPKRVKE
2) MPLRMRNGPQFHHPSSASSHPFSSSSAHHRYADTHDRPG
425
1
472
39

Molecular Recognition Features

MoRF SequenceStartStop
1) LEKWYYNTI
2) LPDDSLLRPPKRVKE
360
458
368
472