<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02191
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MDNPSDPPLDEIQWHSPQLIHEMGGLHSNTILFYFAESPFFERTSNNAVIMSQAMNNMSMYHFIQTREAFEGRLKTMSGLEFIVGEEPAESGPGMGTGVWVIRKQTRRKRYQEADEITVHASYFVVNENIYMAPTLADILAARIMSISSAIAKALPAAEAARRWRPSGGHSYRPPVVAATGPARALQAARARMQDSKEGTPASGATSKSATAPAPRNIEELSLERSAEEAFWVHMRHGGEYLDENPITGRPGEFHLSSTGRKPAMAPQANKAPTGISAMTGPPRLNTKVDDKKDGKAEKAPRSAMPKPKRKKSKLGGTATRTPTAA |
Length | 326 |
Position | Head |
Organism | Beauveria bassiana D1-5 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.575 |
Instability index | 58.44 |
Isoelectric point | 9.58 |
Molecular weight | 35552.93 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02191
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 105.89| 33| 79| 166| 201| 1
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166- 201 (56.98/39.18) PSGGhsyRPPV..VAATG..PARALQAARARMQDSK.EGTP
246- 283 (48.91/25.70) PITG...RPGEfhLSSTGrkPAMAPQANKAPTGISAmTGPP
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