<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02142

Description "Mediator complex, subunit Med10"
SequenceMAPVTLKTVDDDLKDVIQHLFEIQSAVHGYLGPETQHELVRKIKNLTVALSTLSTHTQLPPTQENQPDTNTDPSNPSLASIQLPPEIIDYVDSARNPDIYTREFVELVQRGNQDLRGKREAFASFRDVLAREMRSAMPECRGEVDRVVAATGGVVDRPDGVAGDAATMTMFDAARHVRPLKLWLTSLNEYPEVQWMELISEQEFPDLMNHNANSKEPIGGSVPTNHRIAELEQENEILRRKCAQLRGNNTTSAGRIQSEPEHSVTSESTPRTPRTPLPFSRIAGIGLSRNDSPSTSTRDASHPEVPENDRRNTSLYHGPTSTVYDYTSPNHSEQNRLGQWNEEGTRHFLFSQTARQRQLEPLNLAAGKLDFDGIDPEIGMHLLSIYWSRQLYTAQIIYRPAFMRDMACGGPYFSKLLLNAIFFVVSKHCDRPELRSDPNDITTAGWKFRQRFTYLLRDCFDKSEITTLQALLIMSNALFSRCDERSLSWLYAGNAFNMFIDLGLHVLPSVDSIPAEELEIRKRVLWGAYLIDKIQCLFQGRPPLLNRVNLRASLDFLDDYDELEPFQDITYMAIKPRGVVPSLNVSLLTNLCDLTTIVERVLREIYSESRESSIVHRANISEEIKSQLKTWRQNLPLRLDYLSFPDQAVLLPQSACLLALFNVLIILVHRPLIIGHDGVINSTTAHESVNACTAAANQIVQILHDYSQHFSLSSAPYMLSYATYISATIHARIVAQKGSNSTVFQSLLLCRNILVEHTRLYSAAEKARENLDKLITHLGISATDENLRTGSSGGSENTFPSEHMLVDESMNVARESGVADRALEFGSSLLNLELSDLDLEAIAQGFQVDVESHSFWNSLV
Length860
PositionMiddle
OrganismPenicillium expansum (Blue mold rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium.
Aromaticity0.07
Grand average of hydropathy-0.308
Instability index45.74
Isoelectric point5.42
Molecular weight96699.04
Publications
PubMed=25338147

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
DNA binding	GO:0003677	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02142
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.74|      16|      22|      58|      73|       6
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   58-   73 (31.11/17.94)	QLPPTQENQPDTNTDP
   82-   97 (29.64/16.77)	QLPPEIIDYVDSARNP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02142 with Med10 domain of Kingdom Fungi
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