<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02131
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MDSPNEPPLDEIQWRSPQILAGMGGLHSNTILFYFAESPFFERTSNNAVVMSQAMSNMSMYHFIQTREAFEGRLKTMSGLEFTVAEEPAESGPGMGTGVWVIRKQTRRKRYQEDDEIVVHSTYFVVGENIYMAPTLADILASRIMTISSAIAKALPAAEAARKWRPSLGHVYNLPGSQPATTTTRNLESTVATPAPAPATEAAPPPAVTQKADELSLERAAEEAFMVHMRHGGEYLDENPITGRPGEFHLTSTGRKPVLPPQDKQTPGIGTMNGPSLPGKDESKKEGRADKPSKSPGIPKPKRKKSRLGGGRTPAAS |
Length | 317 |
Position | Head |
Organism | Torrubiella hemipterigena |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Clavicipitaceae> Torrubiella.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.554 |
Instability index | 59.85 |
Isoelectric point | 8.65 |
Molecular weight | 34453.66 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP02131
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 49.63| 14| 16| 168| 181| 2
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168- 181 (25.94/13.18) LGHVYNLPGSQPAT
187- 200 (23.69/11.47) LESTVATPAPAPAT
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.20| 24| 149| 68| 94| 4
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68- 94 (33.22/34.10) EAFEGRLKtmSGLEFtVAEEPAESGPG
223- 246 (46.97/33.14) EAFMVHMR..HGGEY.LDENPITGRPG
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