<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02074

Description Uncharacterized protein
SequenceMGDGNNSNRGLVSANAANRNNNNNNGSHHKKPEWLQQYDLIGKIGEGTYGLVFLAKIKPPSPSRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKANHPLNQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEQGVVKIADFGLARIYQAPLKPLFENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKGPPNPFQLDQLDKIFKVLGHPTIEKWPTLANLPNWQQDVQHIQGHKYDNAGLYNVVHLSPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRLEPLPGYNALVPNQPGEKVINYPTRPVDTTTDFEGTTSLQPSQTVTSGNAVNMQGGHMARSVPRAMGVGMPRMPHQSMAAYNLASQAGMGMNPGGIPMQRGVSSQAHQQQQVILPSRNNKDVTEWFQESLRLLLG
Length485
PositionKinase
OrganismCucumis sativus (Cucumber)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.08
Grand average of hydropathy-0.433
Instability index38.08
Isoelectric point8.92
Molecular weight54280.33
Publications
PubMed=19881527
PubMed=19495411
PubMed=20565788
PubMed=22047402

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02074
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.94|      30|      42|     177|     208|       1
---------------------------------------------------------------------------
  177-  208 (47.53/41.61)	LVMGEGEEQGVVKIADFGLarIYQA..PLKPLFE
  222-  253 (49.40/36.08)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPLFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.87|      15|      37|     398|     412|       2
---------------------------------------------------------------------------
  398-  412 (28.18/16.44)	GNAVNMQGGHMARSV
  438-  452 (30.68/18.52)	GMGMNPGGIPMQRGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.35|      24|      37|     328|     353|       3
---------------------------------------------------------------------------
  328-  353 (32.29/33.43)	KMLEYdPRKRITAAQALEHEyFRLEP
  368-  391 (42.07/30.19)	KVINY.PTRPVDTTTDFEGT.TSLQP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02074 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMGMNPGGIPMQRGVSSQAHQQQQVILPSRNNK
2) MGDGNNSNRGLVSANAANRNNNNNNGSHHKKP
3) PNQPGEKVINYPTRPVDTTTDFEGTTSLQPSQTVTSGNAVNMQGGHMARSVPRAMGVGMPRMPHQSMAAYNLASQ
438
1
362
470
32
436










Molecular Recognition Features






MoRF SequenceStartStop




1) SRGKSIAIKKFKQSK
63
77