<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02069

Description Heat shock protein 70
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPINTVFDAKRLIGRRFSDSSVQSDIKLWPFKVIPGPGDKPMIIVSYKGEEKQFAAEEISSMVLIKMREIAEAYLGSTVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFKRKHKKDISGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSTVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKEEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYAYNMRNTVNDEKIGAKLSPADKKKIDDAIEQSIQWLDANQLAEADEFEDKMKELESICNPIIAKMYQGAGADMGGGADDSAPSGGSGAGPKIEEVD
Length647
PositionUnknown
OrganismCucumis sativus (Cucumber)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Cucurbitales> Cucurbitaceae> Benincaseae> Cucumis.
Aromaticity0.06
Grand average of hydropathy-0.403
Instability index34.67
Isoelectric point5.17
Molecular weight70868.43
Publications
PubMed=19881527
PubMed=19495411
PubMed=20565788
PubMed=22047402

Function

Annotated function
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central
GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP02069
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.46|      50|      74|     412|     466|       1
---------------------------------------------------------------------------
  412-  466 (75.22/57.80)	AGGVMTVLIPRNTTipTKKEQVFSTysdNQPGVLIQ......VYEGERTRTRDNNLLGKFE
  488-  543 (75.24/44.04)	ANGILNVSAEDKTT..GQKNKITIT...NDKGRLSKeeiekmVQEAEKYKSEDEEHKKKVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.11|      45|     189|     170|     218|       4
---------------------------------------------------------------------------
  170-  218 (62.52/51.73)	GLNVMRIINePTaAAIAYGLDKKATSV.GEKNVLIFDLggGTFDVSLLTI
  362-  407 (71.59/43.29)	GKELCKSIN.PD.EAVAYGAAVQAAILsGEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.89|      16|      21|      13|      32|       5
---------------------------------------------------------------------------
   13-   28 (32.80/29.13)	DLG..TTYSCVGVWQHDR
   35-   52 (25.09/10.88)	DQGnrTTPSYVAFTDTER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     251.53|      80|     288|     274|     354|       6
---------------------------------------------------------------------------
  274-  354 (130.08/84.83)	ERAKRTLSSTAQTTIEiDSLYEGIDFY..STITRA.RFEELNMDLFRKCMEPVEKCLRDAKMD.KSTVHDVVLVGGSTRIPKVQQ
  562-  645 (121.45/74.93)	EKIGAKLSPADKKKID.DAIEQSIQWLdaNQLAEAdEFEDKMKELESICNPIIAKMYQGAGADmGGGADDSAPSGGSGAGPKIEE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP02069 with Med37 domain of Kingdom Viridiplantae

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