<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP02014

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAFYTEKVKDTLEQAAAESQLKMCLERLGKMLSSTKNRALIHIAKLEETSSWSAVEQSLVKLGENLNSLSNSQLRSRADDCISLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEDVNCAFVLKLTPLLDKADQRCNCNCMDLLLQECSKQGLLSEANMNNLIDKRAADRQHAPHLKSAENANIQPNPGLILRAEPTVTNILKGLLGVLGHMLSGKSLELLLAAAAATGKLKSFARKFIKLNEFTKQINGEGSKGAPVRALLFDISFLMLCHVAQTYGSEVILSESSPAGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEVCLSISAAILEILNAWENSVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSMGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSHSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPNRSMSTSLSASQLHAVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length973
PositionTail
OrganismCharadrius vociferus (Killdeer) (Aegialitis vocifera)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Charadriiformes> Charadriidae> Charadrius.
Aromaticity0.07
Grand average of hydropathy0.027
Instability index46.73
Isoelectric point7.48
Molecular weight108928.14
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP02014
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.25|      29|      32|     146|     174|       1
---------------------------------------------------------------------------
  146-  174 (46.92/31.56)	LEQAAAESQLKMCLERLGKMLSSTKNRAL
  180-  208 (43.42/28.60)	LEETSSWSAVEQSLVKLGENLNSLSNSQL
  416-  435 (22.92/11.25)	.........LKGLLGVLGHMLSGKSLELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     223.12|      62|     194|     688|     760|       2
---------------------------------------------------------------------------
  563-  635 (67.79/37.75)	LSISAAILEIL.........NAW..ENSVLTFESIqkitdnikgkvcsMAVCAVAWLVAHVRMLGLDEREKSlQMI.....RQLATpLY....
  685-  757 (97.35/77.73)	LPPKKPIKEVLtsvftkvleKGWvdSHSIHIFDTL.............LHMGGVYWFCNNLVKELLKETRKE.HTL.....RAVEL.LYAIFC
  758-  800 (57.97/31.27)	LDMQQL...........................TL.............TLLG.......HILPNLLTDSSKW.HTLmdppgKALAK.L.SVWC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.28|      11|     194|     317|     335|       3
---------------------------------------------------------------------------
  294-  305 (16.15/ 6.03)	PEG....TEELKwTAF
  321-  335 (17.12/14.23)	PQGekdfTEDVN.CAF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP02014 with Med24 domain of Kingdom Metazoa
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