<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP01992

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRIREHNWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length186
PositionUnknown
OrganismTinamus guttatus (White-throated tinamou)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Palaeognathae> Tinamiformes> Tinamidae> Tinamus.
Aromaticity0.07
Grand average of hydropathy-0.975
Instability index50.62
Isoelectric point5.78
Molecular weight21419.65
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP01992
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.35|      18|      18|       3|      20|       1
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    3-   20 (31.30/20.55)	KPVRLKE.RKLTFDPMTGQ
   22-   40 (25.05/15.23)	KPLTQKDpLQVEIPALTEQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP01992 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRI
2) VRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNW
107
5
141
63










Molecular Recognition Features






MoRF SequenceStartStop




1) GVKPVRLKERKLTFDPMTG
2) LNILPYVCL
1
177
19
185